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Uptown Manhattan, Manhattan, NY Office Space for Rent

  • 75 West 125th Street - New York
    75 West 125th Street, Harlem, New York, NY 10027
    For Lease $25 - $47/Sqft/Year
    Property
    • Office
    Availability
    • 2 Spaces
    • 12,100 Sqft
  • 2108-2118 7th Avenue - New York
    2108 7th Avenue, Harlem, New York, NY 10027
    For Lease $48/Sqft/Year
    Property
    • Office
    Availability
    • 1 Space
    • 6,008 Sqft
  • 2212 3rd Avenue - New York
    2212 3rd Avenue, East Harlem, New York, NY 10035
    For Lease $36/Sqft/Year
    Property
    • Office
    Availability
    • 1 Space
    • 12,000 Sqft
  • 516 & 518 West 181st Street - New York
    518 West 181st Street, Washington Heights, New York, NY 10033
    For Lease $35/Sqft/Year
    Property
    • Office
    Availability
    • 1 Space
    • 11,250 Sqft
  • The Corn Exchange Building - New York
    81 East 125th Street, East Harlem, New York, NY 10035
    For Lease $45 - $125/Sqft/Year
    Property
    • Office
    Availability
    • 5 Spaces
    • 21,250 Sqft
  • 126 East 126th Street & 135 East 125th Street - New York
    126 East 126th Street, East Harlem, New York, NY 10035
    For Lease $150/Sqft/Year
    Property
    • Office
    Availability
    • 2 Spaces
    • 2,600 Sqft
  • Harlem Center - New York
    125 West 125th Street, Harlem, New York, NY 10027
    For Lease Contact for pricing
    Property
    • Office
    Availability
    • 1 Space
    • 23,000 Sqft
  • 1751 Park Avenue - New York
    1751 Park Avenue, East Harlem, New York, NY 10035
    For Lease Contact for pricing
    Property
    • Office
    Availability
    • 1 Space
    • 28,539 Sqft
  • 203 West 125th Street - New York
    203 West 125th Street, Harlem, New York, NY 10027
    For Lease Contact for pricing
    Property
    • Office
    Availability
    • 1 Space
    • 1,500 Sqft
  • The Lee Building - New York
    1825 Park Avenue, East Harlem, New York, NY 10035
    For Lease Contact for pricing
    Property
    • Office
    Availability
    • 2 Spaces
    • 1,820 Sqft
  • 5073 Broadway - New York
    5073 Broadway, Inwood, New York, NY 10034
    For Lease Contact for pricing
    Property
    • Office
    Availability
    • 1 Space
    • 15,000 Sqft
  • 215 West 125th Street - New York
    215 West 125th Street, Harlem, New York, NY 10027
    For Lease Contact for pricing
    Property
    • Office
    Availability
    • 1 Space
    • 3,208 Sqft
  • Gotham Plaza - New York
    159 East 125th Street, East Harlem, New York, NY 10035
    For Lease Contact for pricing
    Property
    • Office
    Availability
    • 4 Spaces
    • 12,830 Sqft
  • 2123 2nd Avenue - New York
    2123 2nd Avenue, East Harlem, New York, NY 10029
    For Lease Contact for pricing
    Property
    • Office
    Availability Contact for availability
  • 2389 Adam Clayton Powell - New York
    2389 Adam Clayton Powell, Harlem, New York, NY 10030
    For Lease Contact for pricing
    Property
    • Mixed Use
    Availability
    • 3 Spaces
    • 23,511 Sqft
  • 126 East 126th Street - New York
    126 East 126th Street, East Harlem, New York, NY 10035
    For Lease Contact for pricing
    Property
    • Office
    Availability
    • 1 Space
    • 100 Sqft
  • The Lee Building - New York
    1825 Park Avenue, East Harlem, New York, NY 10035
    For Lease Contact for pricing
    Property
    • Office
    Availability
    • 9 Spaces
    • 36,876 Sqft
  • 1950 Amsterdam Ave - New York
    1950 Amsterdam Ave, Washington Heights, New York, NY 10032
    For Sale Contact for pricing
    Property
    • Office
    Availability Contact for availability
  • 2410 Amsterdam Avenue - New York
    2410 Amsterdam Avenue, Washington Heights, New York, NY 10033
    For Lease Contact for pricing
    Property
    • Office
    Availability
    • 1 Space
    • 8,750 Sqft
  • The Mink Building - New York
    1361 Amsterdam Avenue, Harlem, New York, NY 10027
    For Lease Contact for pricing
    Property
    • Office
    Availability
    • 6 Spaces
    • 61,641 Sqft

Uptown Manhattan, Manhattan, NY Office Space Listings

Our current local inventory includes 41 listings. Explore options of office spaces for rent in Uptown Manhattan, Manhattan, NY across all local neighborhoods and submarkets. Listings presented on our network comprise a wide variety of sizes, as well as an abundance of property classes, amenities and location advantages. Access property details and listing information; get contact details and pricing; and find highlights and points of interest in the region.

Easy-to-use search tools and filters allow you to quickly and conveniently browse our Uptown Manhattan, Manhattan, NY office space for rent listings. Navigate the interactive map to view office listings by ZIP code, neighborhood or radius. Or, browse along a corridor or route of interest with the “current view” mode. Check out similar office spaces in the area and find your perfect place.

Top 10 Largest Office Buildings

in Uptown Manhattan

Office building Address Sqft Year built
The Interchurch Center 475 Riverside Drive, 10115 604,557 1958
Harlem Center 125 West 125th Street, 10027 272,000 2001
55 West 125th Street 55 West 125th Street, 10027 215,000 1974
The Malt House 461 West 126th Street, 10027 200,000 2019
215 West 125th Street 215 West 125th Street, 10027 175,844 1971
Theresa Towers 2090 Adam Clayton Powell Jr. Blvd, 10027 163,440 1970
The Mink Building 1361 Amsterdam Avenue, 10027 150,000 1998
1090 Amsterdam Avenue 1090 Amsterdam Avenue, 10025 149,348 1968
The Lee Building 1825 Park Avenue, 10035 138,156 1901
The Lee Building 1825 Park Avenue, 10035 134,754 1901

Largest Office Properties Recently Completed

in Uptown Manhattan

Office building Address Sqft Year built
74 Wadsworth Avenue 74 Wadsworth Avenue, 10033 65,000 2020
114 West 125th Street 114 West 125th Street, 10027 43,702 2020
The Malt House 461 West 126th Street, 10027 200,000 2019
The Corn Exchange Building 81 East 125th Street, 10035 35,000 2015
Columbia University Medical Center Campus - 51 Audubon Avenue 51 Audubon Avenue, 10032 30,280 2011
The Sweets Building 423 West 127th Street, 10027 51,000 2009
Alianza Dominicana Triangle Building 530 West 166th Street, 10032 48,000 2009
4055 10th Avenue 4055 10th Avenue, 10034 60,000 2007
1751 Park Avenue 1751 Park Avenue, 10035 28,539 2007
374-376 West 125th Street 374 West 125th Street, 10027 124,576 2003

News

RREEF and Cadence Partners’ Turnpike Commerce Center is open for business. Transwestern to lead management and leasing for the brand new Miami office space, available for immediate occupancy.

Extensive renovation and redevelopment work at historic Tammany Hall is finally complete. Marketed as 44 Union Square, the property offers exceptionally located Manhattan office space for rent.

KBS closes third San Jose office sale in four months, marking strong demand on the office market, despite ongoing pandemic.