Durham, NC Commercial Real Estate for Lease
Search 271 commercial real estate listing(s) for lease in Durham, NC, including the latest local availabilities across all property types.
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68 TW Alexander Drive, Durham, NCSpace Type- Private Offices
For Lease-
From $700/month
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201 West Main Street #100, Durham, NC -
701 West Main Street, Durham, NC -
112 Broadway Street #B, Durham, NC -
Looking for more specific results? Choose your preferred property type

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3211 Shannon Road, Durham, NCSpace Type- Private Offices
For Lease-
From $550/month
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324 Blackwell Street #900, Durham, NC
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701 William Vickers Ave, Downtown Durham, Durham, NC
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5107 Southpark Dr, Darby Glen, Durham, NCSpace Type
- Office
For Lease- $22.00 - $23.00/SF/YR
2 spaces available / 490 - 1,657 SF -
1800 TW Alexander Dr, Research Triangle Park, Durham, NC
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4340 Silicon Drive, Research Triangle Park, Durham, NC
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324 Blackwell St, Downtown Durham, Durham, NC
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5116 North Roxboro Street, Old Farm, Durham, NC
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7080 NC Hwy 751, The Landing at Southpoint, Durham, NCSpace Type
- Retail
For Lease- $25.00/SF/YR
1 space available / 1,433 SF -
733 Foster St, Old North Durham, Durham, NCSpace Type
- Office
For Lease- $26.95/SF/YR
3 spaces available / 1,777 - 2,276 SF -
1620 Guess Rd, West Murray - Broad, Durham, NC
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700 W Main St, Warehouse District, Durham, NCSpace Type
- Office
For Lease- $30.00/SF/YR
2 spaces available / 2,196 - 5,747 SF -
4001 E NC Hwy 54, Research Triangle Park, Morrisville, NC
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5826 Fayetteville Road, Folkestone, Durham, NCSpace Type
- Office
For Lease- $20.00 - $25.00/SF/YR
3 spaces available / 965 - 2,044 SF -
4018 Patriot Drive, Research Triangle Park, Durham, NC
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441 South Dillard Street, Downtown Durham, Durham, NC
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4102 South Miami Blvd, Research Triangle Park, Durham, NC
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1001 Hill Drive, Research Triangle Park, Durham, NC
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2525 Whilden Dr, Wynterfield, Durham, NC
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3300 & 3204 North Duke Street, Stadium Heights, Durham, NC
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15 TW Alexander Drive, Durham, NC
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5450 New Hope Commons Dr, Garret Farms - Porchlight - Hartley, Durham, NC
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4401 N Roxboro St, Horton Hills, Durham, NC
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4220 NC Hwy 55, Copper Creek, Durham, NCSpace Type
- Office
For Lease- $22.00/SF/YR
1 space available / 2,860 SF -
1000 W Main St, Trinity Park, Durham, NCSpace Type
- Office
For Lease- $29.50/SF/YR
1 space available / 4,100 SF -
805 S Briggs Ave, North Carolina Central University, Durham, NC
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110 W Main St, Downtown Durham, Durham, NCSpace Type
- Office
For Lease- $25.00/SF/YR
1 space available / 7,306 SF -
2700 Angier Avenue, Amberlynn Valley, Durham, NCSpace Type
- Industrial
For Lease- $0.80/SF/MO
1 space available / 12,500 SF