St Lucie County, FL Commercial Real Estate for Lease
Search 96 commercial real estate listing(s) for lease in St Lucie County, FL, including the latest local availabilities across all property types and find helpful local stats in the Market Overview section below.
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1901 SW Biltmore St, Thornhill, Port Saint Lucie, FLSpace Type
- Industrial
For Lease- $1,000.00/MO
1 space available / 1,000 SF -
2401 Frist Boulevard Unit #1-2, Villages of Longwood, Fort Pierce, FLSpace Type- Office
For Lease- $26.00/SF/YR
1 space available / 2,500 SF -
301 Florida Ave, Indian Hills, Fort Pierce, FLSpace Type- Industrial
For Lease- $15.00/SF/YR
1 space available / 7,500 SF -
870-910 St Lucie W Blvd, Lake Forest Pointe, Port St. Lucie, FLSpace Type
- Retail
For Lease- $45.00/SF/YR
1 space available / 2,496 SF -

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130 South Indian River Drive #202, Fort Pierce, FLSpace Type- Private Offices
For Lease-
From $489/month
Space for 1 to 15 people -
1380 Southwest Import Drive, Gatlin Commons, Port St. Lucie, FL -
1309 SW Gatlin Boulevard, Oak Hammock, Port St. Lucie, FL -
301 Florida Ave, Indian Hills, Fort Pierce, FLSpace Type- Industrial
For Lease- $15.00/SF/YR
1 space available / 7,500 SF -
1801 South 23rd Street 3, Villages of Longwood, Fort Pierce, FLSpace Type- Office
For Lease- $23.00/SF/YR
1 space available / 1,734 SF -
1900 Nebraska Ave #1, Villages of Longwood, Fort Pierce, FLSpace Type- Health Care
For Lease- $3,700.00/MO
1 space available / 2,100 SF -
1401-1421 Southwest Biltmore Street, River Park, Port St. Lucie, FLSpace Type- Industrial
For Lease- $1,300.00/SF/MO
2 spaces available / 1,000 SF -
1801 SE Hillmoor Drive A-102, Downtown Port St. Lucie, Port Saint Lucie, FLSpace Type- Office
For Lease- $24.00/SF/YR
1 space available / 1,530 SF -
10111 U.S. 1, Morningside, Port St. Lucie, FLSpace Type- Retail
For Lease- $175,000.00/YR
1 space available / 4,352 SF -
713 Angle Rd, Sunland Gardens, Fort Pierce, FLSpace Type- Land
For Lease- $4,000.00/MO
1 space available / 89,733 SF -
2222 Colonial Rd 200, River's Edge, Fort Pierce, FLSpace Type- Office
For Lease- $16.50/SF/YR
1 space available / 5,400 SF -
7041 & 7043 S US Highway 1, River Park, Port St. Lucie, FLSpace Type- Office
For Lease- $23.00/SF/YR
2 spaces available / 2,242 - 2,979 SF -
2095 NW Commerce Lakes Dr, Reserve Commerce Park, Port Saint Lucie, FLSpace Type- Flex Space
For Lease- $19.50/SF/YR
2 spaces available / 11,827 SF -
584 Northwest University Boulevard, St. Lucie West, Port St. Lucie, FLSpace Type- Office
For Lease- $27.00/SF/YR
1 space available / 4,200 SF -
870 St. Lucie W Blvd, Lake Forest Pointe, Port St. Lucie, FLSpace Type
- Health Care, Retail
For Lease- $30.00 - $45.00/SF/YR
3 spaces available / 1,965 - 3,437 SF -
870-910 SW St. Lucie Blvd., Lake Forest Pointe, PSL, FLSpace Type- Retail
For Lease- $45.00/SF/YR
1 space available / 2,496 SF -
870 St. Lucie W Blvd, Lake Forest Pointe, Port St. Lucie, FL -
8443 S US 1, River Park, Port St. Lucie, FLSpace Type- Retail
For Lease- $15.75/SF/YR
1 space available / 2,500 SF -
NWC of Becker Rd & SW Village Pkwy, Southern Grove, Port St Lucie, FL -
900 Virginia Ave, River's Edge, Fort Pierce, FLSpace Type- Office
For Lease- $18.00/SF/YR
1 space available / 4,100 SF -
7630 S US Highway 1, Spanish Lakes, Port St. Lucie, FLSpace Type- Retail
For Lease- $23.00 - $24.00/SF/YR
4 spaces available / 928 - 1,849 SF -
Crosstown Pkwy, Southern Grove, Port St. Lucie, FL -
1260 SE Industrial Blvd, Port St. Lucie Industrial Park, Port Saint Lucie, FLSpace Type- Industrial
For Lease- $1,450.00/SF/MO
1 space available / 1,000 SF -
211 Orange Ave, Downtown Fort Pierce, Fort Pierce, FLSpace Type- Retail
For Lease- $19.00/SF/YR
1 space available / 2,000 SF -
921 Avenue D, Avenue D, Fort Pierce, FLSpace Type- Office, Retail
For Lease- $13.85/SF/YR
2 spaces available / 650 SF -
482 NW Lake Whitney Pl, St. Lucie West, Port Saint Lucie, FLSpace Type- Industrial
For Lease- $19.00/SF/YR
1 space available / 1,776 SF -
8241 Business Park Dr, River Park, Port Saint Lucie, FLSpace Type- Industrial
For Lease- $18.00/SF/MO
1 space available / 2,100 SF -
1102 S Us Highway 1, Indian Hills, Fort Pierce, FLSpace Type- Retail
For Lease- $16.00/SF/YR
1 space available / 20,736 SF