San Diego, CA Commercial Real Estate for Lease
Search 1,019 commercial real estate listing(s) for lease in San Diego, CA, including the latest local availabilities across all property types and find helpful local stats in the Market Overview section below.
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600 B Street, Core - Columbia, San Diego, CA -
10275 Science Center Dr., University City, San Diego, CASpace Type- Unassigned
For Lease- $63.00/SF/YR
1 space available / 74,695 SF -
1249 F Street, East Village, San Diego, CA -
5910 Pacific Center Blvd., Sorrento Valley, San Diego, CA -
Looking for more specific results? Choose your preferred property type

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401 B Street, Core - Columbia, San Diego, CASpace Type- Office
For Lease- $2.20/SF/MO
18 spaces available / 1,670 - 22,982 SF -
9920 Pacific Heights Blvd, Sorrento Valley, San Diego, CA -
7995 Armour Street, Kearny Mesa, San Diego, CA -
10398 Pacific Center Ct., Sorrento Valley, San Diego, CA -
9888 Carroll Centre Road, Mira Mesa, San Diego, CASpace Type- Office
For Lease- $2.00/SF/MO
1 space available / 1,516 SF -
2675 Customhouse Court, Otay Mesa, San Diego, CASpace Type- Industrial
For Lease- $1.40 - $15.00/SF/YR
2 spaces available / 2,602 - 11,373 SF -
10616 Scripps Summit Court, Sabre Springs, San Diego, CA -
9389 Waples Street, Sorrento Valley, San Diego, CA -
12812 Rancho Penasquitos Blvd, Rancho Penasquitos, San Diego, CASpace Type- Retail
For Lease- $2.30/SF/MO
1 space available / 1,164 SF -
13275 Black Mtn. Rd, Rancho Penasquitos, San Diego, CA -
4305 University Avenue, Castle, San Diego, CA -
9410 Carroll Park Dr., Sorrento Valley, San Diego, CA -
8885 Rio San Diego Dr., Mission Valley East, San Diego, CASpace Type- Office
For Lease- $34.20/SF/YR
12 spaces available / 1,087 - 10,304 SF -
9619 Chesapeake Drive, Kearny Mesa, San Diego, CASpace Type- Office
For Lease- $2.80/SF/MO
1 space available / 1,784 SF -
5401-5605 Balboa Avenue, Clairemont Mesa East, San Diego, CA -
10578 Science Center Dr., University City, San Diego, CA -
8690 Kerns Street, Otay Mesa, San Diego, CASpace Type- Industrial
For Lease- $1.15/SF/MO
1 space available / 24,905 SF -
12812 Rancho Penasquitos Blvd, Rancho Penasquitos, San Diego, CASpace Type- Retail
For Lease- $27.60/SF/YR
1 space available / 1,164 SF -
501 W. Broadway, Marina, San Diego, CA -
3900 5th Avenue, Hillcrest, San Diego, CA -
1855 Dornoch Ct., Otay Mesa, San Diego, CA -
8990 Miramar Road, Miramar, San Diego, CASpace Type- Office, Retail
For Lease- $1.65 - $2.25/SF/MO
8 spaces available / 1,350 - 38,507 SF -
2020 Piper Ranch Road, Otay Mesa, San Diego, CA -
9950 Scripps Lake Drive, Scripps Ranch, San Diego, CASpace Type- Industrial
For Lease- $1.60/SF/MO
1 space available / 5,230 SF -
8925 Carroll Way, Miramar, San Diego, CA -
12625 High Bluff Drive, Carmel Valley, San Diego, CA -
7310 Miramar Road, Miramar, San Diego, CASpace Type- Office, Retail
For Lease- $1.95 - $2.50/SF/MO
14 spaces available / 243 - 43,482 SF -
925 Waterfront Pl., Marina, San Diego, CA