22 S Main St

For Lease

22 S Main St, Greenville, SC 29601

The total number of office spaces available at 22 S Main St is 1. Leasing opportunities in the building include general office. There is a total of 10,308 square feet of space currently available for rent at this address. Of this, the minimum divisible area is 10,308 square feet.

Space Available For Lease 1

Contacts

Edward Wilson

Trinity Partners

Property Details

  • Property Type Office - General Office
  • Property Size 41,494 SF
  • Units 4
  • Lot Size 0.25 Acre
  • Building Class A
  • Date Updated May 15, 2026
In the heart of Downtown Greenville overlooking Main Street$22.50/SF Full Service Sublease
Want more info on this listing?

Reach out to the broker for more info on lease terms and amenities

Highlights

  • Great security/access controls
  • In the heart of Downtown Greenville on Main Street
  • Master lease expiration: 12/1/2026 with two 5-year renewal options; potential for direct lease
  • Shared balcony overlooking Main Street
  • Shared gym within building
  • Space includes: one large boardroom, one large conference room, 9 private offices, and a full kitchen
  • Turnkey space, high level finishes on top floor with elevator access

Getting around

  • 85/100

    Walk Score ®

  • 32/100

    Transit Score ®

  • 79/100

    Bike Score ®

Powered by Walk Score ®

Location

  • City Greenville, SC
  • Neighborhood Downtown Greenville
  • Zip Code 29601
  • Market Greenville

Points of Interest

  • Fast Charger

    0.16 miles

  • QuikTrip

    0.70 miles

  • Marathon

    0.73 miles

  • ChargePoint

    0.77 miles

  • Shell

    0.82 miles

  • Spinx

    1.22 miles

  • Texaco

    1.29 miles

  • Circle K

    1.57 miles

  • GT's Express Mart

    1.64 miles

  • Harvey's

    1.71 miles

  • West Washington Parking Deck

    0.06 miles

  • Poinsett Parking Garage

    0.08 miles

  • South Spring Street Garage

    0.11 miles

  • City Hall Visitor parking

    0.13 miles

  • First Presbyterian Church Parking

    0.14 miles

  • Richardson Street Parking

    0.15 miles

  • River Street Garage

    0.18 miles

  • BS UMC Parking

    0.20 miles

  • Condustrial Parking

    0.20 miles

  • The Westin Poinsett Hotel

    0.09 miles

  • Aloft

    0.09 miles

  • SpringHill Suites

    0.15 miles

  • Courtyard Greenville Downtown

    0.16 miles

  • AC Hotel

    0.22 miles

  • Hyatt Place

    0.26 miles

  • Hyatt Regency Greenville

    0.26 miles

  • Embassy Suites

    0.27 miles

  • Hampton Inn & Suites Greenville-Downtown-RiverPlace

    0.32 miles

  • Home2 Suites

    0.33 miles

  • Mast General Store

    0.14 miles

  • Publix

    0.31 miles

  • Harris Teeter

    1.10 miles

  • The Fresh Market

    2.17 miles

  • Educators' Marketplace

    2.19 miles

  • Saigon Market

    2.39 miles

  • Deal Mart

    2.42 miles

  • Food Lion

    2.44 miles

  • ALDI

    2.58 miles

  • Ingles

    2.61 miles

22 S Main St Listing Brief

  • Leasing rates here can depend on a variety of factors, including the quality rating of the property (property class or building class), the position of the available space within the building, any unique attributes that the listed space may include, as well as on the availability of on-site or nearby amenities. Reach out using the contact form available on this page to schedule a tour or to get more detailed information on the most modern facilities and amenities that 22 S Main St has to offer.

  • See the listing area details for information and ratings regarding the degree of walkability in the neighborhood, the accessibility and frequency of public transit options, as well as the level of availability and quality of biking infrastructure in the area. What’s more, you can use the interactive map for a good overview of the area. Location details also include a breakdown of distance from the property to several essential amenities and points of interest, which may include parking facilities, fuel stations, stores, or hotels.

  • This property is in the Downtown Greenville neighborhood of Greenville and located within zip code 29601.

    22 S Main St is rated class A. The building includes 41,494 square feet, of which 10,308 square feet is rentable office space.

Contact Listing Broker
Edward Wilson

Trinity Partners

  1. 1Main information
  2. 2Extra information
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.