Portsmouth, NH Commercial Real Estate for Lease
Search 47 commercial real estate listing(s) for lease in Portsmouth, NH, including the latest local availabilities across all property types and find helpful local stats in the Market Overview section below.
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330 Borthwick Avenue, Meadowbrook, Portsmouth, NHSpace Type- Office
For Lease- $18.00 - $19.50/SF/YR
1 space available / 1,705 SF -
875 Greenland Road, Meadowbrook, Portsmouth, NHSpace Type- Office
For Lease- $12.50 - $15.00/SF/YR
1 space available / 2,500 SF -
100 New Hampshire Avenue, Sherburne, Portsmouth, NHSpace Type- Industrial
For Lease- $16.50/SF/YR
1 space available / 71,370 SF -
135 McDonough Street, Portsmouth, NHParlor Coworking
Parlor CoworkingSpace Type- Private Offices
For Lease-
From $650/month
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Looking for more specific results? Choose your preferred property type

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500 Maplewood Avenue, Bersum Gardens, Portsmouth, NHSpace Type- Office
For Lease- $10.48/SF/YR
1 space available / 8,202 SF -
72 Mirona Rd, Elwyn Park, Portsmouth, NHSpace Type- Retail
For Lease- $17.50/SF/YR
2 spaces available / 2,050 - 3,331 SF -
230 Commerce Way, Wentworth Acres, Portsmouth, NHSpace Type- Office
For Lease- $19.50/SF/YR
1 space available / 4,930 SF -
2454 Lafayette Road, Hillcrest, Portsmouth, NH -
111 New Hampshire Avenue, Sherburne, Portsmouth, NHSpace Type- Industrial
For Lease- $14.00/SF/YR
1 space available / 56,488 SF -
375 Banfield Rd, Elwyn Park, Portsmouth, NH -
500 Maplewood Avenue, Bersum Gardens, Portsmouth, NHSpace Type- Retail
For Lease- $10.71/SF/YR
1 space available / 3,921 SF -
215 Commerce Way, Wentworth Acres, Portsmouth, NHSpace Type- Office
For Lease- $16.50/SF/YR
1 space available / 12,336 SF -
111 Maplewood Ave, Suite F, North Mill Pond, Portsmouth, NHSpace Type- Office
For Lease- $28.00/SF/YR
2 spaces available / 2,116 - 2,777 SF -
100 Borthwick Ave, Meadowbrook, Portsmouth, NHSpace Type- Office
For Lease- $28.00/SF/YR
5 spaces available / 900 - 5,610 SF -
270 West Rd Ste 3, Elwyn Park, Portsmouth, NHSpace Type- Industrial
For Lease- $15.00/SF/YR
1 space available / 4,994 SF -
273 Corporate Drive, Sherburne, Portsmouth, NHSpace Type- Office
For Lease- $19.50/SF/YR
1 space available / 16,027 SF -
4 Greenleaf Woods Drive, Elwyn Park, Portsmouth, NHSpace Type- Office
For Lease- $445.00/MO
1 space available / 100 SF -
405 The Hill, North Mill Pond, Portsmouth, NHSpace Type- Office
For Lease- $850.00/MO
1 space available / 350 SF -
11 Portwalk Pl, Portsmouth, NHPortwalk Place Cowork
Portwalk Place CoworkSpace Type- Private Offices
For Lease-
From $1,500/month
Space for up to 2 people -
125 Aviation Ave, Sherburne, Portsmouth, NHSpace Type- Industrial
For Lease- $10.00/SF/YR
2 spaces available / 5,320 - 20,500 SF -
96 Penhallow Street, North Mill Pond, Portsmouth, NHSpace Type- Office
For Lease- $3,700.00/MO
1 space available / 1,300 SF -
280 Heritage Avenue, Hillcrest, Portsmouth, NHSpace Type- Industrial
For Lease- $14.00/SF/YR
1 space available / 5,100 SF -
1390 Lafayette Road, Elwyn Park, Portsmouth, NH -
170 Commerce Way Suite 200, Portsmouth, NHRegus - Portsmouth
RegusSpace Type- Private Offices
For Lease-
From $569/month
Space for 1 to 15 people -
210 Commerce Way, Wentworth Acres, Portsmouth, NHSpace Type- Office
For Lease- $19.50/SF/YR
2 spaces available / 1,854 - 3,172 SF -
325 Corporate Drive, Sherburne, Portsmouth, NH -
755 Banfield Rd, Hillcrest, Portsmouth, NHSpace Type
- Office
For Lease- $12.50/SF/YR
1 space available / 2,875 SF -
42 Cutts Street, Bersum Gardens, Portsmouth, NHSpace Type- Other
For Lease Contact for pricing -
501 Islington St, North Mill Pond, Portsmouth, NH
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170 West Rd, Elwyn Park, Portsmouth, NHSpace Type
- Office
For Lease- $29.85/SF/YR
2 spaces available / 120 - 402 SF -
210 West Rd, Elwyn Park, Portsmouth, NHSpace Type
- Office
For Lease- $1,800.00/MO
1 space available / 1,000 SF -
1000 Market Street, Building 2, Bersum Gardens, Portsmouth, NHSpace Type
- Office
For Lease- $23.00/SF/YR
1 space available / 5,100 SF