301 Broadway St

For Lease

301 Broadway St, Cape Girardeau, MO 63701

The total number of office spaces available at 301 Broadway St is 5. Leasing opportunities in the building include street retail, shared space and creative office. There is a total of 12,975 square feet of space currently available for rent at this address. Of this, the minimum divisible area is 1,250 square feet.

Space Available For Lease 5

Contacts

Matt Huber

Lorimont Commercial Real Estate

Property Details

  • Property Type Office - General Office
  • Property Size 21,507 SF
  • Building Class A
  • Date Updated Jun 7, 2026
301 Broadway is centrally located in the heart of downtown Cape Girardeau, one of Southeast Missouri’s most vibrant and walkable business districts. The property sits among a dynamic mix of restaurants, retail, and entertainment venues, offering convenience and energy for both employees and clients. The historic Missourian Building has long been a cornerstone of the community and continues to serve as a hub for business and media activity. Its prime location places tenants within walking distance of key amenities and just minutes from major transportation routes. Strategically positioned between St. Louis and Memphis, Cape Girardeau provides regional accessibility while maintaining a strong local workforce and business environment. Nearby parking and multiple access points make commuting and client visits simple and efficient.MAKE SURE YOU CLICK THE "Spaces" TAB Position your business in one of downtown Cape Girardeau's most recognizable landmark buildings. Located at the highly visible corner of Broadway and Lorimier, 301 Broadway offers a rare opportunity to lease flexible office and commercial space in the center of the city's business, entertainment, and dining district. Multiple suites are currently available ranging from approximately 1,250 SF to 13,500 SF, providing options for small professional offices, growing businesses, regional headquarters, training facilities, coworking concepts, and mixed-use commercial users. Existing spaces are primarily configured for office use and feature a combination of private offices, conference rooms, collaborative work areas, and support spaces. Tenants will benefit from a prominent downtown location within walking distance of restaurants, retail, financial institutions, government offices, and the riverfront. Whether you're seeking a single suite or a larger multi-floor presence, 301 Broadway offers flexibility, visibility, and a prestigious business address in the heart of Cape Girardeau.
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Highlights

  • Convenient access to government offices, professional services, and regional employers
  • Corner location offering excellent visibility and exposure
  • Easy access to major regional transportation corridors
  • Existing office buildouts with private offices, conference rooms, and open workspaces
  • Flexible leasing options available
  • Historic building with distinctive architectural character
  • Ideal for professional office, corporate headquarters, medical office, educational, nonprofit, and service-based users
  • Located within Cape Girardeau's central business district
  • Multiple floor plans available to accommodate a variety of users
  • Opportunity for suite customization based on tenant needs
  • Professional image and prestigious downtown business address
  • Prominent location in the heart of Downtown Cape Girardeau
  • Suites available from 1,250 SF to 13,500 SF
  • Walkable to restaurants, coffee shops, retail, banking, and entertainment

Attachments

Getting around

  • 76/100

    Walk Score ®

  • 48/100

    Bike Score ®

Powered by Walk Score ®

Location

  • City Cape Girardeau, MO
  • Zip Code 63701

Points of Interest

  • Gordonville

    9.11 miles

  • Jackson

    9.40 miles

  • Iron Moountain Junction

    9.71 miles

  • Kidd's gas station

    1.75 miles

  • Rhodes

    3.01 miles

  • Mobil

    3.42 miles

  • Rhodes Travel Center

    5.07 miles

  • Over the road truck parking

    5.00 miles

  • Church overflow parking

    5.90 miles

  • Courtyard Cape Girardeau Downtown

    0.08 miles

  • Town House Inn Cape Girardeau

    1.87 miles

  • Budget Inn Motel & Restaurant

    2.77 miles

  • Pear Tree Inn Cape Girardeau Medical Center

    3.03 miles

  • Candlewood Suites Cape Girardeau

    3.06 miles

  • Hampton Inn Cape Girardeau I-55 East

    3.06 miles

  • Holiday Inn Express Cape Girardeau

    3.07 miles

  • Auburn Place Hotel & Suites

    3.15 miles

  • Drury Plaza Hotel Cape Girardeau Conference Center

    3.23 miles

  • Pear Tree Inn Cape Girardeau West

    3.28 miles

  • Walmart Neighborhood Market

    1.56 miles

  • ALDI

    1.62 miles

  • Kmart

    1.82 miles

  • Schnucks

    1.82 miles

  • West Park Mall

    2.78 miles

  • TJ Maxx

    3.24 miles

  • Target

    3.27 miles

  • Walmart Supercenter

    3.58 miles

  • Kohl's

    3.61 miles

  • Bob's Food Liner

    6.28 miles

301 Broadway St Listing Brief

  • Leasing rates here can depend on a variety of factors, including the quality rating of the property (property class or building class), the position of the available space within the building, any unique attributes that the listed space may include, as well as on the availability of on-site or nearby amenities. Reach out using the contact form available on this page to schedule a tour or to get more detailed information on the most modern facilities and amenities that 301 Broadway St has to offer.

  • See the listing area details for information and ratings regarding the degree of walkability in the neighborhood, the accessibility and frequency of public transit options, as well as the level of availability and quality of biking infrastructure in the area. What’s more, you can use the interactive map for a good overview of the area. Location details also include a breakdown of distance from the property to several essential amenities and points of interest, which may include parking facilities, fuel stations, stores, or hotels.

  • 301 Broadway St is rated class A. The building includes 21,507 square feet, of which 12,975 square feet is rentable office space.

Contact Listing Broker
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