Port St. Lucie, FL Commercial Real Estate for Lease
Search 70 commercial real estate listing(s) for lease in Port St. Lucie, FL, including the latest local availabilities across all property types.
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201 SW Port St Lucie Blvd, Thornhill, Port Saint Lucie, FLSpace Type- Office
For Lease- $26.00 - $71.40/SF/YR
2 spaces available / 100 - 900 SF -
6901 - 6945 NW LTC Parkway, Torino, Port Saint Lucie, FLSpace Type- Industrial
For Lease- $16.00/SF/YR
2 spaces available / 2,225 - 4,344 SF -
7121 S US Highway 1, River Park, Port Saint Lucie, FLSpace Type- Retail
For Lease- $12.00 - $17.00/SF/YR
4 spaces available / 6,480 - 21,126 SF -
7448 S. Federal Hwy 1, Spanish Lakes, Port St. Lucie, FLSpace Type- Office
For Lease- $23.11/SF/YR
1 space available / 1,350 SF -

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11325 Southwest Discovery Way, Southern Grove, Port St. Lucie, FL -
584 NW University Blvd Suite 350 584 Northwest University Boulevard, Port St. Lucie, FL -
870 St. Lucie W Blvd, Lake Forest Pointe, Port St. Lucie, FLSpace Type
- Health Care
For Lease- $45.00/SF/YR
1 space available / 3,437 SF -
300 NW Bethany Drive # 320, St. Lucie West, Port St. Lucie, FLSpace Type- Office
For Lease- $18.00/SF/YR
1 space available / 2,000 SF -
SW Port St Lucie Blvd, Oak Hammock, Port Saint Lucie, FLSpace Type- Retail
For Lease- $31.00/SF/YR
1 space available / 1,165 SF -
761 E Prima Vista Blvd, River Park, Port St. Lucie, FLSpace Type- Office
For Lease- $35.50/SF/YR
1 space available / 1,425 SF -
Tuckpoint Business Park - 660-664 NW Enterprise Dr, St. Lucie West, Port St. Lucie, FL -
7444 S. Federal Highway, Spanish Lakes, Port Saint Lucie, FLSpace Type- Office
For Lease- $26.40/SF/YR
1 space available / 1,000 SF -
1857 SE Port St Lucie Blvd, Morningside, Port St. Lucie, FLSpace Type- Office
For Lease- $2.10/SF/MO
1 space available / 1,058 SF -
6632 S US Highway 1, Spanish Lakes, Port St. Lucie, FLSpace Type- Retail
For Lease- $25.00/SF/YR
1 space available / 1,255 SF -
145 NW Central Park Plz, Port Saint Lucie, FL 34986-2482, St. Lucie West, Port Saint Lucie, FLSpace Type- Office
For Lease- $1,350.00 - $4,277.50/MO
2 spaces available / 432 - 1,711 SF -
460-466 SW Port St Lucie Blvd, Oak Hammock, Port Saint Lucie, FLSpace Type- Retail
For Lease- $14.00 - $29.00/SF/YR
3 spaces available / 654 - 1,739 SF -
10570 S US Highway 1, Downtown Port St. Lucie, Port Saint Lucie, FLSpace Type- Office
For Lease- $21.00/SF/YR
1 space available / 1,295 SF -
1260 SE Industrial Blvd, Port St. Lucie Industrial Park, Port Saint Lucie, FLSpace Type- Industrial
For Lease- $1,450.00/MO
1 space available / 1,000 SF -
7041 & 7043 S US Highway 1, River Park, Port St. Lucie, FLSpace Type- Office
For Lease- $23.00/SF/YR
2 spaces available / 2,242 - 2,979 SF -
8443 S US 1, River Park, Port St. Lucie, FLSpace Type- Retail
For Lease- $15.75/SF/YR
1 space available / 2,500 SF -
870-910 SW St. Lucie Blvd., Lake Forest Pointe, PSL, FLSpace Type- Retail
For Lease- $45.00/SF/YR
1 space available / 2,496 SF -
1801 SE Hillmoor Drive A-102, Downtown Port St. Lucie, Port Saint Lucie, FLSpace Type- Office
For Lease- $28.00/SF/YR
1 space available / 1,530 SF -
7630 South U.S. Highway 1, Spanish Lakes, Port St. Lucie, FLSpace Type- Retail
For Lease- $23.00 - $24.00/SF/YR
4 spaces available / 928 - 1,849 SF -
585 NW Lake Whitney Place, St. Lucie West, Port St. Lucie, FLSpace Type- Office
For Lease- $25.00/SF/YR
1 space available / 6,619 SF -
870 St. Lucie W Blvd, Lake Forest Pointe, Port St. Lucie, FL -
2100 SE Hillmoor Drive Unit 204A, Eastlake Village, Port St. Lucie, FLSpace Type- Office
For Lease- $29.20/SF/YR
1 space available / 940 SF -
12051 SW Tom Mackie Blvd, Southern Grove, Port St. Lucie, FL -
7434 S Federal Hwy, Spanish Lakes, Port St. Lucie, FLSpace Type- Office
For Lease- $23.11/SF/YR
1 space available / 1,350 SF -
870-910 SW St. Lucie West Blvd, Westbrook Isles, Port St. Lucie, FL -
525 NW Lake Whitney Place, St. Lucie West, Port St. Lucie, FLSpace Type- Office
For Lease- $21.00/SF/YR
2 spaces available / 1,133 SF -
120-128 SW Chamber Court, Lake Charles, Port Saint Lucie, FLSpace Type- Office
For Lease- $22.00/SF/YR
1 space available / 4,020 SF -
1801 Southeast Hillmoor Drive-Unit A-107, Downtown Port St. Lucie, Port St. Lucie, FLSpace Type- Office
For Lease- $28.00/SF/YR
1 space available / 1,530 SF