Port St. Lucie, FL Commercial Real Estate for Lease
Search 71 commercial real estate listing(s) for lease in Port St. Lucie, FL, including the latest local availabilities across all property types.
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Tuckpoint Business Park - 660-664 NW Enterprise Dr, St. Lucie West, Port St. Lucie, FL -
7630 S US Highway 1, Spanish Lakes, Port St. Lucie, FLSpace Type- Retail
For Lease- $23.00/SF/YR
4 spaces available / 928 - 1,849 SF -
1309 SW Gatlin Boulevard, Oak Hammock, Port St. Lucie, FL -
12051 SW Tom Mackie Blvd, Southern Grove, Port St. Lucie, FL -
Looking for more specific results? Choose your preferred property type

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10111 U.S. 1, Morningside, Port St. Lucie, FLSpace Type- Retail
For Lease- $175,000.00/YR
1 space available / 4,352 SF -
7448 S. Federal Hwy 1, Spanish Lakes, Port St. Lucie, FLSpace Type- Office
For Lease- $22.67/SF/YR
1 space available / 1,350 SF -
1260 SE Industrial Blvd, Port St. Lucie Industrial Park, Port Saint Lucie, FLSpace Type- Industrial
For Lease- $1,450.00/MO
1 space available / 1,000 SF -
7041 & 7043 S US Highway 1, River Park, Port St. Lucie, FLSpace Type- Office
For Lease- $23.00/SF/YR
2 spaces available / 2,242 - 2,979 SF -
2095 NW Commerce Lakes Dr, Reserve Commerce Park, Port Saint Lucie, FLSpace Type- Flex Space
For Lease- $19.50/SF/YR
2 spaces available / 11,827 SF -
1801 SE Hillmoor Drive A-102, Downtown Port St. Lucie, Port Saint Lucie, FLSpace Type- Office
For Lease- $28.00/SF/YR
1 space available / 1,530 SF -
6901 - 6945 NW LTC Parkway, Torino, Port Saint Lucie, FLSpace Type- Industrial
For Lease- $16.00/SF/YR
2 spaces available / 2,225 - 4,344 SF -
567 NW Lake Whitney Place, St. Lucie West, Port St. Lucie, FL -
870-910 St Lucie W Blvd, Lake Forest Pointe, Port St. Lucie, FLSpace Type
- Retail
For Lease- $45.00/SF/YR
1 space available / 2,496 SF -
7444 S. Federal Highway, Spanish Lakes, Port Saint Lucie, FLSpace Type- Office
For Lease- $25.20/SF/YR
1 space available / 1,000 SF -
7434 S Federal Hwy, Spanish Lakes, Port St. Lucie, FLSpace Type- Office
For Lease- $22.67/SF/YR
1 space available / 1,350 SF -
300 NW Bethany Drive # 320, St. Lucie West, Port St. Lucie, FLSpace Type- Office
For Lease- $18.00/SF/YR
1 space available / 2,000 SF -
584 Northwest University Boulevard, St. Lucie West, Port St. Lucie, FLSpace Type- Office
For Lease- $27.00/SF/YR
1 space available / 4,200 SF -
872 SE Becker Road, Tesoro, Port Saint Lucie, FLSpace Type- Retail
For Lease- $25.00/SF/YR
1 space available / 1,125 SF -
7121 S US Highway 1, River Park, Port Saint Lucie, FLSpace Type- Retail
For Lease- $12.00 - $14.00/SF/YR
3 spaces available / 8,300 - 21,126 SF -
1401-1421 Southwest Biltmore Street, River Park, Port St. Lucie, FLSpace Type- Industrial
For Lease- $1,300.00/SF/MO
2 spaces available / 1,000 SF -
584 NW University Blvd Suite 350 584 Northwest University Boulevard, Port St. Lucie, FL -
525 NW Lake Whitney Place, St. Lucie West, Port St. Lucie, FLSpace Type- Office
For Lease- $21.00/SF/YR
2 spaces available / 1,133 SF -
870-910 SW St. Lucie Blvd., Lake Forest Pointe, PSL, FLSpace Type- Retail
For Lease- $45.00/SF/YR
1 space available / 2,496 SF -
201 SW Port St Lucie Blvd, Thornhill, Port Saint Lucie, FLSpace Type- Office
For Lease Contact for pricing -
870 St. Lucie W Blvd, Lake Forest Pointe, Port St. Lucie, FLSpace Type
- Health Care
For Lease- $45.00/SF/YR
1 space available / 3,437 SF -
8443 S US 1, River Park, Port St. Lucie, FLSpace Type- Retail
For Lease- $15.75/SF/YR
1 space available / 2,500 SF -
585 NW Lake Whitney Place, St. Lucie West, Port St. Lucie, FLSpace Type- Office
For Lease- $25.00/SF/YR
1 space available / 6,619 SF -
10570 S US Highway 1, Downtown Port St. Lucie, Port Saint Lucie, FLSpace Type- Office
For Lease- $21.00/SF/YR
1 space available / 1,295 SF -
870 St. Lucie W Blvd, Lake Forest Pointe, Port St. Lucie, FL -
SW Port St Lucie Blvd, Oak Hammock, Port Saint Lucie, FLSpace Type- Retail
For Lease- $22.00 - $31.00/SF/YR
2 spaces available / 1,165 - 2,124 SF -
460-466 SW Port St Lucie Blvd, Oak Hammock, Port Saint Lucie, FLSpace Type- Retail
For Lease- $14.00 - $29.00/SF/YR
3 spaces available / 654 - 1,739 SF -
Crosstown Pkwy, Southern Grove, Port St. Lucie, FL