The Cove At Oyster Point 5

For Lease

181 Oyster Point Blvd, S San Francisco, CA 94080

The total number of office spaces available at The Cove At Oyster Point 5 is 4. Leasing opportunities in the building include office. There is a total of 143,644 square feet of space currently available for rent at this address. Of this, the minimum divisible area is 33,771 square feet.

Space Available For Lease 4

Contacts

Marc Pope

Cushman & Wakefield

Property Details

  • Property Type Office
  • Property Size 164,909 SF
  • # of Floors 5
  • Year Built 2020
  • Date Updated Aug 11, 2026
Discover the advantages of establishing your business at The Cove at Oyster Point, a feature-packed Class-A campus situated at the epicenter of the South San Francisco life science cluster. 181 Oyster Point presents 164,150 square feet of cutting-edge lab and office space. Abundant on-site and nearby amenities enhance the work environment, while seamless accessibility is ensured through convenient connections to US-101 and shuttle services to BART, Caltrain, and Ferry service.
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Highlights

  • 150 square feet of cutting-edge lab and office space. Abundant on-site and nearby amenities enhance the work environment
  • a feature-packed Class-A campus situated at the epicenter of the South San Francisco life science cluster. 181 Oyster Point presents 164
  • and Ferry service.
  • Caltrain
  • Sublessor: PfizerDiscover the advantages of establishing your business at The Cove at Oyster Point
  • while seamless accessibility is ensured through convenient connections to US-101 and shuttle services to BART

Getting around

  • 43/100

    Walk Score ®

  • 59/100

    Bike Score ®

Powered by Walk Score ®

Location

  • City S San Francisco, CA
  • Neighborhood Oyster Point
  • Zip Code 94080
  • Market San Francisco

Points of Interest

  • Long Term Parking

    1.95 miles

  • San Bruno

    2.13 miles

  • South San Francisco

    2.77 miles

  • West Field Road

    2.86 miles

  • Taxi Stand at SFO, Domestic Terminal 3 (Arrivals Level in front of Door 5, 6, 7, 8, 9, 10)

    3.12 miles

  • Terminal 3

    3.15 miles

  • San Francisco International Airport (SFO)

    3.20 miles

  • Taxi Stand at SFO, Domestic Terminal 2 (Arrivals Level in front of Door 1, 2, 3, 4)

    3.21 miles

  • San Francisco International Airport

    3.22 miles

  • Taxi Stand at International Arrivals SFO

    3.25 miles

  • Blink

    0.18 miles

  • Shell

    0.62 miles

  • Golden Gate Gasoline

    0.73 miles

  • Fathom Marine

    0.84 miles

  • Speedway

    0.87 miles

  • 76

    0.99 miles

  • Chico's

    1.00 miles

  • True Zero

    1.23 miles

  • Valero

    1.33 miles

  • EV Range

    1.41 miles

  • ParkSFO

    1.63 miles

  • United Airlines East Parking Lot

    1.75 miles

  • SFO Long-Term Parking Garage #1

    1.85 miles

  • SFO Long-Term Parking Garage #2

    1.93 miles

  • Cell Phone Waiting Lot

    2.01 miles

  • SFO TNC Staging Lot 3

    2.05 miles

  • SFO Long-Term Parking

    2.05 miles

  • Charter Bus Staging Lot

    2.06 miles

  • Worksite Labs Testing Site at SFO

    2.09 miles

  • Taxi Staging Lot

    2.10 miles

  • AC Hotel

    0.17 miles

  • Sonesta Select San Francisco Airport Oyster Point Waterfront

    0.24 miles

  • Sonesta ES Suites

    0.29 miles

  • Larkspur Landing South San Francisco

    0.36 miles

  • Days Inn by Wyndham San Francisco S/Oyster Point Airport

    0.41 miles

  • Hilton Garden Inn San Francisco Airport North

    0.43 miles

  • Home2 Suites by Hilton San Francisco Airport North

    0.52 miles

  • Hampton Inn San Francisco Airport

    0.60 miles

  • Embassy Suites by Hilton San Francisco Airport

    0.65 miles

  • Homewood Suites by Hilton San Francisco Airport-North

    0.70 miles

  • La Hacienda Market

    0.83 miles

  • Safeway

    2.11 miles

  • Lucky

    2.20 miles

  • Target

    2.21 miles

  • Marshalls

    2.22 miles

  • The Shops at Tanforan

    2.27 miles

  • Smart & Final

    2.29 miles

  • JCPenney

    2.29 miles

  • Pacific Supermarket

    2.36 miles

  • Besan’s International Market

    2.85 miles

181 Oyster Point Blvd Listing Brief

  • Leasing rates here can depend on a variety of factors, including the quality rating of the property (property class or building class), the position of the available space within the building, any unique attributes that the listed space may include, as well as on the availability of on-site or nearby amenities. Reach out using the contact form available on this page to schedule a tour or to get more detailed information on the most modern facilities and amenities that 181 Oyster Point Blvd has to offer.

  • See the listing area details for information and ratings regarding the degree of walkability in the neighborhood, the accessibility and frequency of public transit options, as well as the level of availability and quality of biking infrastructure in the area. What’s more, you can use the interactive map for a good overview of the area. Location details also include a breakdown of distance from the property to several essential amenities and points of interest, which may include parking facilities, fuel stations, stores, or hotels.

  • This property is in the Oyster Point neighborhood of S San Francisco and located within zip code 94080.

    The building includes 164,909 square feet, of which 143,644 square feet is rentable office space.

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