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South San Francisco, CA Office Space for Rent

  • SPACES OYSTER POINT - San Francisco
    Coworking
    Spaces - California, South San Francisco - Oyster Point Suite 120, San Francisco, CA
    Services
    • Virtual Office
    • Open Workspace
    • Private Office
    • Dedicated Desk
    Amenities
    View Details
  • Gateway of Pacific III - South San Francisco
    700 Gateway Blvd, The East Side, South San Francisco, CA
    For Lease
    • Contact for pricing
    Property
    • Office
    • 360,000 SF
    Availability
    • 1 Space
    • 350,000 SF
    Year Built
    • 2022
    View Details
  • 6000 Shoreline - S San Francisco
    6000 Shoreline Ct, Paradise Valley, S San Francisco, CA
    For Lease
    • Contact for pricing
    Property
    • Office
    • 142,024 SF
    Availability
    • 1 Space
    • 8,945 SF
    Year Built
    • 2001
    View Details
  • Oyster Point Marina Plaza II - S San Francisco
    395 Oyster Point Blvd, Oyster Point, S San Francisco, CA
    For Lease
    • Contact for pricing
    Property
    • Office
    • 232,733 SF
    Availability
    • 14 Spaces
    • 86,318 SF
    Year Built
    • 1986
    View Details
  • Britannia Pointe Grand - South San Francisco
    250 East Grand Avenue, The East Side, South San Francisco, CA
    For Lease
    • Contact for pricing
    Property
    • Office
    • 630,500 SF
    Availability
    • 2 Spaces
    • 74,724 SF
    Year Built
    • 1989
    View Details
  • Gateway Commons - 651 Gateway - Redevelopment - South San Francisco
    651 Gateway Blvd, Gateway, South San Francisco, CA
    For Lease
    • $7/SF/YR
    Property
    • Office
    • 300,010 SF
    Availability
    • 1 Space
    • 325,215 SF
    Year Built
    • 2022
    View Details
  • 5000 Shoreline Court - South San Francisco
    5000 Shoreline Court, Paradise Valley, South San Francisco, CA
    For Lease
    • Contact for pricing
    Property
    • Office
    • 138,399 SF
    Availability
    • 1 Space
    • 48,000 SF
    Year Built
    • 2000
    View Details
  • 701 Gateway - S San Francisco
    701 Gateway Blvd, Gateway, S San Francisco, CA
    For Lease
    • $39/SF/YR
    Property
    • Office
    • 176,036 SF
    Availability
    • 1 Space
    • 4,293 SF
    Year Built
    • 1999
    View Details
  • Gateway Commons - S San Francisco
    611 Gateway Blvd, Gateway, S San Francisco, CA
    For Lease
    • Contact for pricing
    Property
    • Office
    • 260,337 SF
    Availability
    • 2 Spaces
    • 38,182 SF
    Year Built
    • 2002
    View Details
  • Oyster Point Marina Plaza I - S San Francisco
    400 Oyster Point Blvd, Oyster Point, S San Francisco, CA
    For Lease
    • $45/SF/YR
    Property
    • Office
    • 231,769 SF
    Availability
    • 16 Spaces
    • 29,159 SF
    Year Built
    • 1986
    View Details
  • Britannia Oyster Point I - C - South San Francisco
    1140 Veterans Blvd, Oyster Point, South San Francisco, CA
    For Lease
    • Contact for pricing
    Property
    • Office
    • 67,000 SF
    Availability
    • 3 Spaces
    • 69,058 SF
    Year Built
    • 2003
    View Details
  • 7000 Shoreline Court - South San Francisco
    7000 Shoreline Court, Paradise Valley, South San Francisco, CA
    For Lease
    • $84/SF/YR
    Property
    • Office
    • 136,395 SF
    Availability
    • 3 Spaces
    • 35,435 SF
    Year Built
    • 2003
    View Details
  • The Gateway North Campus - 951 Gateway Blvd - South San Francisco
    951 Gateway Blvd, Gateway, South San Francisco, CA
    For Lease
    • Contact for pricing
    Property
    • Office
    • 59,816 SF
    Availability
    • 2 Spaces
    • 39,000 SF
    Year Built
    • 2002
    View Details
  • 453 Forbes Blvd - South San Francisco
    453 Forbes Blvd, The East Side, South San Francisco, CA
    For Lease
    • Contact for pricing
    Property
    • Industrial
    • 38,102 SF
    Availability
    • 11 Spaces
    • 37,598 SF
    Year Built
    • 1967
    View Details
  • Gateway Crossing - 1 Corporate Drive - South San Francisco
    1 Corporate Drive, Gateway, South San Francisco, CA
    For Lease
    • Contact for pricing
    Property
    • Office
    • 71,479 SF
    Availability
    • 1 Space
    • 36,000 SF
    Year Built
    • 1999
    View Details
  • The Gateway Technology Center - 630 Gateway Blvd - South San Francisco
    630 Gateway Blvd, The East Side, South San Francisco, CA
    For Lease
    • $66/SF/YR
    Property
    • Office
    • 50,160 SF
    Availability
    • 1 Space
    • 61,160 SF
    Year Built
    • 2001
    View Details
  • 90 South Spruce - S San Francisco
    90 Spruce Ave, S., Orange Park, S San Francisco, CA
    For Lease
    • $25.8 - $33/SF/YR
    Property
    • Industrial
    • 36,410 SF
    Availability
    • 4 Spaces
    • 5,202 SF
    Year Built
    • 1900
    View Details
  • Genesis - South Tower - South San Francisco
    1 Tower Place, Paradise Valley, South San Francisco, CA
    For Lease
    • Contact for pricing
    Property
    • Office
    • 324,986 SF
    Availability
    • 1 Space
    • 14,997 SF
    Year Built
    • 2009
    View Details
  • The Gateway North Campus - 901 Gateway Blvd - South San Francisco
    901 Gateway Blvd, Gateway, South San Francisco, CA
    For Lease
    • Contact for pricing
    Property
    • Office
    • 110,428 SF
    Availability
    • 3 Spaces
    • 111,000 SF
    Year Built
    • 2000
    View Details
  • Vantage - Building B - South San Francisco
    494 Forbes Blvd, The East Side, South San Francisco, CA
    For Lease
    • Contact for pricing
    Property
    • Office
    • 188,000 SF
    Availability
    • 6 Spaces
    • 188,000 SF
    Year Built
    • 2022
    View Details

Explore Office Listings in South San Francisco, CA

Our current local inventory includes 39 listings. Explore options of office spaces for rent in South San Francisco, CA across all local neighborhoods and submarkets. Listings presented on our network comprise a wide variety of sizes, as well as an abundance of property classes, amenities and location advantages. Access property details and listing information; get contact details and pricing; and find highlights and points of interest in the region.

Easy-to-use search tools and filters allow you to quickly and conveniently browse our South San Francisco, CA office space for rent listings. Navigate the interactive map to view office listings by ZIP code, neighborhood or radius. Or, browse along a corridor or route of interest with the “current view” mode. Check out similar office spaces in the area and find your perfect place.

Frequently Asked Questions

How many office listings are on the market in South San Francisco, CA?

South San Francisco, CA currently has 39 active office listings and 124 available spaces, totaling 3,519,435 square feet. Browse through all of the active listings to find your ideal office space for rent.

What is the minimum/maximum amount of office space you can rent in South San Francisco, CA?

Whether you’re a part of a startup or an established business, the South San Francisco, CA market boasts a wide range of office space availabilities to suit every need.For small businesses and entrepreneurs, the minimum rentable office space in South San Francisco, CA is 675 square feet. At the other end of the spectrum, the largest available office space on the market now is 900,000 square feet.

What is the average size and rental rate for a rentable office space in South San Francisco, CA?

Currently, the average size of rentable office availabilities in South San Francisco, CA is 450,338 square feet, with a mean lease rate of approximately $59.72 per square foot.
To optimize your search, you can filter listings by location, property size, or available space. You can also sort listings from newest to oldest. Property pages will offer details about the year the property was built, as well as its rating, rentable space, lease rate and more.

How do I get an office space in South San Francisco, CA?

First, asses your office space requirements and optimize your search results by using the filters on our website. Next, draw up a shortlist of office spaces that fit your needs and budget. Then, contact the listed broker(s) to schedule a viewing and begin the negotiation process for your lease contract.

What other property types are available for rent in South San Francisco, CA?

In addition to office spaces, there are currently 55 active listings for industrial spaces and 3 active listings for retail spaces in the South San Francisco, CA commercial real estate market.

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