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South San Francisco, CA Office Space for Rent

  • Airport Boulevard - South San Francisco
    11 Airport Blvd, Lindenville, South San Francisco, CA
    For Lease
    • Contact for pricing
    Property
    • Office
    • 52,327 Sqft
    Availability
    • 1 Space
    • 2,054 Sqft
    Year Built
    • 1987
    View Details
  • The Gateway Technology Center - 600 Gateway Blvd - South San Francisco
    600 Gateway Blvd, The East Side, South San Francisco, CA
    For Lease
    • $5.75/Sqft/Month
    Property
    • Office
    • 81,308 Sqft
    Availability
    • 2 Spaces
    • 14,000 Sqft
    Year Built
    • 1998
    View Details
  • 701 Gateway - S San Francisco
    701 Gateway Blvd, Gateway, S San Francisco, CA
    For Lease
    • $39/Sqft/Year
    Property
    • Office
    • 176,036 Sqft
    Availability
    • 1 Space
    • 4,293 Sqft
    Year Built
    • 1999
    View Details
  • 405 Victory Avenue - South San Francisco
    405 Victory Avenue, Lindenville, South San Francisco, CA
    For Lease
    • $16.2 - $18.6/Sqft/Year
    Property
    • Industrial
    • 211,259 Sqft
    Availability
    • 6 Spaces
    • 129,208 Sqft
    Year Built
    • 1958
    View Details
  • 701 Gateway - South San Francisco
    701 Gateway Blvd, Gateway, South San Francisco, CA
    For Lease
    • $54/Sqft/Year
    Property
    • Office
    • 170,323 Sqft
    Availability
    • 2 Spaces
    • 13,709 Sqft
    Year Built
    • 1999
    View Details
  • 270 Lawrence Avenue - South San Francisco
    270 Lawrence Avenue, The East Side, South San Francisco, CA
    For Lease
    • $1.75/Sqft/Month
    Property
    • Industrial
    • 40,000 Sqft
    Availability
    • 1 Space
    • 7,458 Sqft
    Year Built
    • 1962
    View Details
  • The Gateway Technology Center - 650 Gateway Blvd - South San Francisco
    650 Gateway Blvd, The East Side, South San Francisco, CA
    For Lease
    • $66/Sqft/Year
    Property
    • Office
    • 50,400 Sqft
    Availability
    • 1 Space
    • 50,400 Sqft
    Year Built
    • 1999
    View Details
  • 400 Oyster Point Blvd - South San Francisco
    400 Oyster Point Blvd, Oyster Point, South San Francisco, CA
    For Lease
    • $33/Sqft/Year
    Property
    • Office
    • 234,480 Sqft
    Availability
    • 1 Space
    • 2,314 Sqft
    Year Built
    • 1985
    View Details
  • Oyster Point Marina Plaza I - S San Francisco
    400 Oyster Point Blvd, Oyster Point, S San Francisco, CA
    For Lease
    • $40.8 - $42/Sqft/Year
    Property
    • Office
    • 231,769 Sqft
    Availability
    • 15 Spaces
    • 24,691 Sqft
    Year Built
    • 1986
    View Details
  • 2400 Westborough Blvd - South San Francisco
    2400 Westborough Blvd, North Westborough, South San Francisco, CA
    For Lease
    • $2.75/Sqft/Month
    Property
    • Office
    • 32,214 Sqft
    Availability
    • 1 Space
    • 1,011 Sqft
    Year Built
    • 1976
    View Details
  • Genesis - North Tower - South San Francisco
    2 Tower Place, Paradise Valley, South San Francisco, CA
    For Lease
    • $69/Sqft/Year
    Property
    • Office
    • 381,523 Sqft
    Availability
    • 3 Spaces
    • 34,267 Sqft
    Year Built
    • 2018
    View Details
  • Oyster Point Marina Plaza II - S San Francisco
    395 Oyster Point Blvd, Oyster Point, S San Francisco, CA
    For Lease
    • Contact for pricing
    Property
    • Office
    • 232,733 Sqft
    Availability
    • 15 Spaces
    • 88,136 Sqft
    Year Built
    • 1986
    View Details
  • The Gateway Technology Center - 630 Gateway Blvd - South San Francisco
    630 Gateway Blvd, The East Side, South San Francisco, CA
    For Lease
    • $66/Sqft/Year
    Property
    • Office
    • 50,160 Sqft
    Availability
    • 1 Space
    • 61,160 Sqft
    Year Built
    • 2001
    View Details
  • 90 South Spruce - S San Francisco
    90 Spruce Ave, S., Orange Park, S San Francisco, CA
    For Lease
    • $25.8 - $33/Sqft/Year
    Property
    • Industrial
    • 36,410 Sqft
    Availability
    • 4 Spaces
    • 5,202 Sqft
    Year Built
    • 1900
    View Details
  • 7000 Shoreline Court - South San Francisco
    7000 Shoreline Court, Paradise Valley, South San Francisco, CA
    For Lease
    • $84/Sqft/Year
    Property
    • Office
    • 136,395 Sqft
    Availability
    • 2 Spaces
    • 71,865 Sqft
    Year Built
    • 2003
    View Details
  • 100-130 Produce Avenue - South San Francisco
    100 Produce Avenue, Lindenville, South San Francisco, CA
    For Lease
    • $9.6 - $19.5/Sqft/Year
    Property
    • Office
    • 41,448 Sqft
    Availability
    • 2 Spaces
    • 3,917 Sqft
    Year Built
    • 1986
    View Details
  • Britannia Biotech Gateway Center I - 1 Corporate Drive - South San Francisco
    1 Corporate Drive, Gateway, South San Francisco, CA
    For Lease
    • Contact for pricing
    Property
    • Office
    • 71,479 Sqft
    Availability
    • 1 Space
    • 36,000 Sqft
    Year Built
    • 1999
    View Details
  • Britannia Modular Labs I - 285 East Grand Avenue - South San Francisco
    285 East Grand Avenue, The East Side, South San Francisco, CA
    For Lease
    • Contact for pricing
    Property
    • Office
    • 61,770 Sqft
    Availability
    • 1 Space
    • 23,000 Sqft
    Year Built
    • 2006
    View Details
  • The Gateway North Campus - 951 Gateway Blvd - South San Francisco
    951 Gateway Blvd, Gateway, South San Francisco, CA
    For Lease
    • Contact for pricing
    Property
    • Office
    • 59,816 Sqft
    Availability
    • 2 Spaces
    • 39,000 Sqft
    Year Built
    • 2002
    View Details
  • 343 Oyster Point Blvd - South San Francisco
    343 Oyster Point Blvd, Oyster Point, South San Francisco, CA
    For Lease
    • Contact for pricing
    Property
    • Office
    • 53,980 Sqft
    Availability
    • 1 Space
    • 20,315 Sqft
    Year Built
    • 2001
    View Details

Explore Office Listings in South San Francisco, CA

Our current local inventory includes 38 listings. Explore options of office spaces for rent in South San Francisco, CA across all local neighborhoods and submarkets. Listings presented on our network comprise a wide variety of sizes, as well as an abundance of property classes, amenities and location advantages. Access property details and listing information; get contact details and pricing; and find highlights and points of interest in the region.

Easy-to-use search tools and filters allow you to quickly and conveniently browse our South San Francisco, CA office space for rent listings. Navigate the interactive map to view office listings by ZIP code, neighborhood or radius. Or, browse along a corridor or route of interest with the “current view” mode. Check out similar office spaces in the area and find your perfect place.

Frequently Asked Questions

How many office listings are on the market in South San Francisco, CA?

South San Francisco, CA currently has 38 active office listings and 97 available spaces, totaling 2,166,907 square feet. Browse through all of the active listings to find your ideal office space for rent.

What is the minimum/maximum amount of office space you can rent in South San Francisco, CA?

Whether you’re a part of a startup or an established business, the South San Francisco, CA market boasts a wide range of office space availabilities to suit every need.For small businesses and entrepreneurs, the minimum rentable office space in South San Francisco, CA is 667 square feet. At the other end of the spectrum, the largest available office space on the market now is 900,000 square feet.

What is the average size and rental rate for a rentable office space in South San Francisco, CA?

Currently, the average size of rentable office availabilities in South San Francisco, CA is 450,334 square feet, with a mean lease rate of approximately $40.93 per square foot.
To optimize your search, you can filter listings by location, property size, or available space. You can also sort listings from newest to oldest. Property pages will offer details about the year the property was built, as well as its rating, rentable space, lease rate and more.

How do I get an office space in South San Francisco, CA?

First, asses your office space requirements and optimize your search results by using the filters on our website. Next, draw up a shortlist of office spaces that fit your needs and budget. Then, contact the listed broker(s) to schedule a viewing and begin the negotiation process for your lease contract.

What other property types are available for rent in South San Francisco, CA?

In addition to office spaces, there are currently 70 active listings for industrial spaces and 3 active listings for retail spaces in the South San Francisco, CA commercial real estate market.