Charleston, SC Commercial Real Estate for Lease
Search 160 commercial real estate listing(s) for lease in Charleston, SC, including the latest local availabilities across all property types and find helpful local stats in the Market Overview section below.
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634 Orleans Rd, Dupont Area - Orleans, Charleston, SC
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2225 Ashley Crossing Drive, Pierpont, Charleston, SCSpace Type
- Office
For Lease- $25.00/SF/YR
2 spaces available / 200 - 700 SF -
2500 Clements Ferry Rd, Daniel Island, Charleston, SCSpace Type
- Retail
For Lease- $14.12 - $25.00/SF/YR
2 spaces available / 1,700 - 2,800 SF -
Looking for more specific results? Choose your preferred property type

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545 Parkwood Estates Drive, Parkwood - Farmfield, Charleston, SCSpace Type
- Office
For Lease- $4,200.00/MO
1 space available / 1,655 SF -
1567 Meeting Street Rd, Four Mile Hibernian, North Charleston, SC
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151 Market Street, Harleston Village, Charleston, SCSpace Type
- Retail
For Lease- $37.00/SF/YR
1 space available / 1,945 SF -
2276 Savannah Hwy, Savage Road - Citadel Mall, Charleston, SCSpace Type
- Retail
For Lease- $12.00/SF/YR
1 space available / 2,250 SF -
2245 Ashley Crossing Drive, Drayton Quarters - Magwood, Charleston, SC
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1291 Folly Road, Riverland Woods - Dill Tract, Charleston, SC
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1657 Ashley Hall Road, Village Square - Pinecrest Gardens, Charleston, SC
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1890 Sam Rittenberg Blvd, Dupont Area - Orleans, Charleston, SCSpace Type
- Retail
For Lease- $24.00 - $26.00/SF/YR
2 spaces available / 1,200 - 2,473 SF -
1525 Sam Rittenberg Blvd, Charlestowne Estates - Ashley Hall, Charleston, SCSpace Type
- Office
For Lease- $900.00 - $4,195.00/MO
3 spaces available / 250 - 1,525 SF -
1300 Savannah Highway, St. Andrews - Forest, Charleston, SCSpace Type
- Retail
For Lease- $28.00 - $30.00/SF/YR
2 spaces available / 1,250 - 1,600 SF -
51 George Street, Downtown Charleston, Charleston, SCSpace Type
- Retail
For Lease- $45.00/SF/YR
2 spaces available / 1,611 - 2,030 SF -
15 Gamecock Ave, Sandhurst - Governours Point, Charleston, SCSpace Type
- Office
For Lease- $28.00 - $41.67/SF/YR
2 spaces available / 720 - 3,625 SF -
895 Island Park Drive , Daniel Island, Charleston, SCSpace Type
- Office
For Lease- $33.00/SF/YR
2 spaces available / 1,070 - 1,643 SF -
438 King St, Mazyck - Wraggborough, Charleston, SCSpace Type
- Retail
For Lease- $35.00 - $75.00/SF/YR
1 space available / 10,673 SF -
852 Dupont Rd, Dupont Area - Orleans, Charleston, SC
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484 King St, Mazyck - Wraggborough, Charleston, SCSpace Type
- Retail
For Lease- $20.00/SF/YR
1 space available / 3,011 SF -
1064 Gardner Rd suite 207 #207, Charleston, SC
Local Work Club - 1064 Gardner Road
Local Work ClubSpace Type- Memberships
For Lease-
From $115/month
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162 Seven Farms Drive, Daniel Island, Charleston, SC
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1925 Clements Ferry Rd, Daniel Island, Wando, SCSpace Type
- Industrial
For Lease- $25.00/SF/YR
1 space available / 1,500 SF -
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2386 Clements Ferry Road, Daniel Island, Wando, SC
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630 Skylark Drive, Dupont Area - Orleans, Charleston, SCSpace Type
- Retail
For Lease- $25.00/SF/YR
3 spaces available / 1,580 - 6,400 SF -
1013 Physicians Dr, Savage Road - Citadel Mall, Charleston, SC
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14 Farmfield Ave, Parkwood - Farmfield, Charleston, SCSpace Type
- Office
For Lease- $28.00/SF/YR
1 space available / 9,924 SF -
3030 Ashley Town Center Drive, Savage Road - Citadel Mall, Charleston, SCSpace Type
- Office
For Lease- $19.50/SF/YR
1 space available / 3,290 SF -
121 Calhoun Street, Downtown Charleston, Charleston, SCSpace Type
- Office
For Lease- $42.00/SF/YR
1 space available / 2,625 SF -
730 Hopewell Drive, Daniel Island, Charleston, SC
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211 River Landing Drive, Daniel Island, Charleston, SC