South Carolina Commercial Real Estate for Lease
Search 2,400 commercial real estate listing(s) for lease in South Carolina, including the latest local availabilities across all property types.
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83 Mary St, Mazyck - Wraggborough, Charleston, SCSpace Type- Office
For Lease- $35.00/SF/YR
3 spaces available / 1,246 - 1,542 SF -
Webber Rd, Mayo, South Carolina, SC -
300 South St, Simpsonville, SCSpace Type- Office
For Lease- $25.00 - $150.00/SF/YR
6 spaces available / 76 - 2,220 SF -
937 N Pleasantburg Dr, Overbrook, Greenville, SC -
Looking for more specific results? Choose your preferred property type

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1015 Bankton Cir, Hanahan, SC -
121 Trotter Industrial Ln, Saluda, SCSpace Type- Industrial
For Lease- $3.49/SF/YR
1 space available / 108,030 SF -
1311 South Murray Avenue, Anderson, SCSpace Type- Office
For Lease- $1,300.00/MO
1 space available / 1,300 SF -
100 Malibu Dr, Hilltop, Spartanburg, SC -
5409 Platt Springs Road, Lexington, SC -
5055 Edgefield Rd, Trenton, SCSpace Type- Mixed Use
For Lease- $6.25/SF/YR
1 space available / 11,000 SF -
8351 Palmetto Commerce Pkwy, Goose Creek, Ladson, SC -
923 Medical Cir, North End Myrtle Beach, Myrtle Beach, SCSpace Type- Office
For Lease- $22.00/SF/YR
1 space available / 1,368 SF -
1201 Main Street, Downtown Columbia, Columbia, SCSpace Type- Office, Retail
For Lease- $21.50 - $26.50/SF/YR
9 spaces available / 921 - 19,961 SF -
2685 Celanese Rd, Shiland Hills, Rock Hill, SCSpace Type- Retail
For Lease- $15.00 - $27.00/SF/YR
4 spaces available / 1,641 - 6,750 SF -
720 Antioch Drive, Gantt, Greenville, SC -
1071 Harbor Drive, West Columbia, SCSpace Type- Industrial
For Lease- $1,800.00/MO
3 spaces available / 1,500 SF -
716 E Fairfield Rd, Gantt, Greenville, SCSpace Type- Industrial
For Lease- $8.00/SF/YR
1 space available / 2,800 SF -
6406 Garners Ferry Road, Brandon Acres, Columbia, SC -
2720 Commerce Dr, Central Rosewood, Columbia, SCSpace Type- Industrial
For Lease- $6.50/SF/YR
1 space available / 19,266 SF -
3618 Sunset Blvd., West Columbia, SCSpace Type- Office
For Lease- $18.00/SF/YR
1 space available / 1,000 SF -
1045 5th Ave, Maryville - Asleyville, Charleston, SCSpace Type- Industrial
For Lease- $21.00/SF/YR
1 space available / 4,200 SF -
1870 Highway 17 N, Garden City, Surfside Beach, SCSpace Type- Retail
For Lease- $15.00/SF/YR
1 space available / 98,840 SF -
Calhoun Memorial Hwy, Easley, SC -
K Ave, Gaston, South Carolina, SC -
1012 E Shockley Ferry Rd, Anderson, SCSpace Type- Retail
For Lease- $1,500.00/MO
1 space available / 1,800 SF -
5 Enterprise Ln, Hilton Head Island, SC -
145 King Street, Harleston Village, Charleston, SCSpace Type- Office
For Lease- $34.00 - $36.00/SF/YR
6 spaces available / 1,204 - 6,191 SF -
611 Burroughs & Chapin Blvd, Downtown Myrtle Beach, Myrtle Beach, SCSpace Type- Office
For Lease- $27.00/SF/YR
2 spaces available / 1,032 - 4,861 SF -
650 E Fairplay Blvd, Fair Play, SCSpace Type- Industrial
For Lease- $3,800.00/MO
1 space available / 9,100 SF -
355 South Main Street 1st & 2nd Floor, Greenville, SCSpace Type- Private Offices
For Lease-
From $469/month
Space for 1 to 15 people -
201 N Main St, Mauldin, SCSpace Type- Land
For Lease- $110,000.00/YR
1 space available / 60,374 SF -
591 Browns Cove Road, Units H, I, & J, Ridgeland, SC