Syracuse, NY Commercial Real Estate for Lease
Search 95 commercial real estate listing(s) for lease in Syracuse, NY, including the latest local availabilities across all property types and find helpful local stats in the Market Overview section below.
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100 North Salina Street, Downtown Syracuse, Syracuse, NYSpace Type- Office
For Lease- $17.00/SF/YR
1 space available / 6,985 SF -
109 South Warren Street, Downtown Syracuse, Syracuse, NY -
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888 Brighton Avenue East, Outer Comstock, Syracuse, NYSpace Type
- Office
For Lease- $1,875.00/MO
1 space available / 1,600 SF -
Looking for more specific results? Choose your preferred property type

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317 South Salina Street, Downtown Syracuse, Syracuse, NYSpace Type
- Retail
For Lease- $20.50/SF/YR
1 space available / 5,280 SF -
205 South Salina Street, Downtown Syracuse, Syracuse, NYSpace Type
- Office
For Lease- $16.00/SF/YR
1 space available / 4,289 SF -
131 NBT Bank Parkway, Lakefront, Syracuse, NY
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301 West Fayette Street, Downtown Syracuse, Syracuse, NYSpace Type
- Office
For Lease- $16.95/SF/YR
1 space available / 3,800 SF -
185 Ainsley Drive, Outer Comstock, Syracuse, NY
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2401 - 2425 James Street, Eastwood, Syracuse, NY
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964 Spencer Street, Lakefront, Syracuse, NYSpace Type
- Industrial
For Lease- $6.50/SF/YR
2 spaces available / 3,600 - 7,200 SF -
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221 Herald Place, Downtown Syracuse, Syracuse, NY
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745 Hiawatha Blvd W, Lakefront, Syracuse, NY
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4001 E. GENESEE ST, Meadowbrook, Syracuse, NY
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3000-3040 Erie Boulevard East, Salt Springs, Syracuse, NYSpace Type
- Retail
For Lease- $10.00/SF/YR
1 space available / 4,205 SF -
2363 James Street, Eastwood, Syracuse, NY
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811 Genesee St E, Near Eastside Syracuse, Syracuse, NYSpace Type
- Retail
For Lease- $20.00/SF/YR
1 space available / 2,286 SF -
214 Solar Street, Lakefront, Syracuse, NY
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235 Harrison Street, Syracuse, NY
Inspyre Innovation Hub - 235 Harrison Street
Inspyre Innovation Hub -
315 South Crouse Avenue, Near Eastside Syracuse, Syracuse, NY
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476 South Salina Street, Downtown Syracuse, Syracuse, NY
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119 Simon Drive, Salt Springs, Syracuse, NYSpace Type
- Retail
For Lease- $18.50 - $21.00/SF/YR
2 spaces available / 1,767 - 3,350 SF -
112 Dewitt St, Sedgwick, Syracuse, NYSpace Type
- Office
For Lease- $1,400.00/MO
1 space available / 951 SF -
1810 Erie Blvd E, Near Eastside Syracuse, Syracuse, NYSpace Type
- Office
For Lease- $14.00/SF/YR
1 space available / 4,200 SF -
1401 Erie Blvd East, Near Eastside Syracuse, Syracuse, NY
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101 Newbury Hollow Lane, Outer Comstock, Syracuse, NY
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400 South Salina Street, Downtown Syracuse, Syracuse, NY
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304 Hawley Ave, Near Northeast Syracuse, Syracuse, NY
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731 James Street, Near Northeast Syracuse, Syracuse, NY
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936 North Clinton Street, Lakefront, Syracuse, NY