Syracuse, NY Commercial Real Estate for Lease
Search 91 commercial real estate listing(s) for lease in Syracuse, NY, including the latest local availabilities across all property types and find helpful local stats in the Market Overview section below.
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500 Plum Street, Lakefront, Syracuse, NYSpace Type- Office
For Lease- $20.00/SF/YR
1 space available / 7,054 SF -
3522 James Street, Eastwood, Syracuse, NYSpace Type- Office
For Lease Contact for pricing -
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1401 Erie Blvd East, Near Eastside Syracuse, Syracuse, NY
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Looking for more specific results? Choose your preferred property type

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131 NBT Bank Parkway, Lakefront, Syracuse, NY
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303 W Division Street, Lakefront, Syracuse, NYSpace Type
- Office
For Lease- $26.50/SF/YR
1 space available / 5,500 SF -
2401 - 2425 James Street, Eastwood, Syracuse, NY
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140 Intrepid Ln, Outer Comstock, Syracuse, NY
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936 North Clinton Street, Lakefront, Syracuse, NY
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101 Newbury Hollow Lane, Outer Comstock, Syracuse, NY
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124 East Jefferson, Downtown Syracuse, Syracuse, NY
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4001 E. GENESEE ST, Meadowbrook, Syracuse, NY
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3000-3040 Erie Boulevard East, Salt Springs, Syracuse, NYSpace Type
- Retail
For Lease- $10.00/SF/YR
1 space available / 4,205 SF -
119 Simon Drive, Salt Springs, Syracuse, NYSpace Type
- Retail
For Lease- $18.50 - $21.00/SF/YR
2 spaces available / 1,767 - 3,350 SF -
405 Taylor Street West, Southwest Syracuse, Syracuse, NYSpace Type
- Industrial
For Lease- $5.00/SF/YR
1 space available / 17,250 SF -
2140 Erie Blvd E, Salt Springs, Syracuse, NY
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731 James Street, Near Northeast Syracuse, Syracuse, NY
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315 South Crouse Avenue, Near Eastside Syracuse, Syracuse, NY
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964 Spencer Street, Lakefront, Syracuse, NYSpace Type
- Industrial
For Lease- $6.50/SF/YR
2 spaces available / 3,600 - 7,200 SF -
185 Ainsley Drive, Outer Comstock, Syracuse, NY
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171 Marshall Street, University Hill, Syracuse, NYSpace Type
- Retail
For Lease- $75.00 - $125.00/SF/YR
2 spaces available / 3,100 SF -
351 South Warren Street, Syracuse, NY
Commonspace - The Western Union Building
CommonspaceSpace Type- Private Offices
For Lease-
From $500/month
Space for 1 to 5 people -
221 Herald Place, Downtown Syracuse, Syracuse, NY
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221 South Warren Street, Downtown Syracuse, Syracuse, NY
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2105 W Genesee St, Far Westside Syracuse, Syracuse, NY
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235 Harrison Street, Syracuse, NY
Inspyre Innovation Hub - 235 Harrison Street
Inspyre Innovation Hub -
304 Hawley Ave, Near Northeast Syracuse, Syracuse, NY
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231-251 Cortland Ave, Southwest Syracuse, Syracuse, NYSpace Type
- Industrial
For Lease- $15.50/SF/YR
1 space available / 18,338 SF -
2921 Erie Blvd E, Salt Springs, Syracuse, NYSpace Type
- Office
For Lease- $12.00/SF/YR
1 space available / 6,685 SF -
1860 Erie Blvd East, Near Eastside Syracuse, Syracuse, NYSpace Type
- Office
For Lease- $10.00/SF/YR
1 space available / 2,060 SF -
600 North Franklin Street, Lakefront, Syracuse, NY
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215 Fayette Street West, Downtown Syracuse, Syracuse, NYSpace Type
- Office
For Lease- $14.50/SF/YR
1 space available / 4,000 SF