Syracuse, NY Commercial Real Estate for Lease
Search 97 commercial real estate listing(s) for lease in Syracuse, NY, including the latest local availabilities across all property types.
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3522 James st Eastwood/DeWitt, Eastwood, Syracuse, NYSpace Type- Mixed Use
For Lease Contact for pricing -
224 Harrison Street, Downtown Syracuse, Syracuse, NYSpace Type
- Office, Restaurant
For Lease- $12.50 - $16.00/SF/YR
6 spaces available / 500 - 7,677 SF -
301 South Salina Street, Downtown Syracuse, Syracuse, NYSpace Type- Retail
For Lease- $20.00/SF/YR
1 space available / 6,000 SF -
250 Harrison Street, Downtown Syracuse, Syracuse, NYSpace Type- Retail
For Lease- $16.00/SF/YR
1 space available / 2,302 SF -
Looking for more specific results? Choose your preferred property type

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327 West Fayette Street #412, Syracuse, NY -
205 S Salina St, Downtown Syracuse, Syracuse, NY
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235 Harrison Street, Syracuse, NY
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2363 James Street, Eastwood, Syracuse, NY
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112 Wilkinson Street, Westside Syracuse, Syracuse, NYSpace Type
- Office
For Lease- $12.50/SF/YR
2 spaces available / 7,361 - 12,500 SF -
185 Ainsley Drive, Outer Comstock, Syracuse, NY
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301 West Fayette Street, Downtown Syracuse, Syracuse, NYSpace Type
- Office
For Lease- $16.95/SF/YR
1 space available / 3,800 SF -
964 Spencer Street, Lakefront, Syracuse, NYSpace Type
- Industrial
For Lease- $6.50/SF/YR
2 spaces available / 3,600 - 7,200 SF -
1860 Erie Blvd East, Near Eastside Syracuse, Syracuse, NYSpace Type
- Office
For Lease- $10.00/SF/YR
1 space available / 2,060 SF -
4001 E. GENESEE ST, Meadowbrook, Syracuse, NY
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3125 East Genesee Street, Meadowbrook, Syracuse, NYSpace Type
- Office
For Lease- $16.95/SF/YR
1 space available / 2,029 SF -
112 Dewitt St, Sedgwick, Syracuse, NYSpace Type
- Office
For Lease- $1,400.00/MO
1 space available / 951 SF -
131 NBT Bank Parkway, Lakefront, Syracuse, NY
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221 South Warren Street, Downtown Syracuse, Syracuse, NY
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221 Herald Place, Downtown Syracuse, Syracuse, NY
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109 South Warren Street, Downtown Syracuse, Syracuse, NYSpace Type
- Office
For Lease- $18.50 - $240.00/SF/YR
13 spaces available / 549 - 8,502 SF -
2140 Erie Blvd E, Salt Springs, Syracuse, NY
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3000-3040 Erie Boulevard East, Salt Springs, Syracuse, NYSpace Type
- Retail
For Lease- $10.00 - $14.00/SF/YR
2 spaces available / 1,439 - 4,205 SF -
246 East Water Street Syracuse, Downtown Syracuse, Syracuse, NY
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1401 Erie Blvd East, Near Eastside Syracuse, Syracuse, NY
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614 Crouse Avenue South, University Hill, Syracuse, NYSpace Type
- Retail
For Lease- $30.00/SF/YR
1 space available / 2,500 SF -
2105 W Genesee St, Far Westside Syracuse, Syracuse, NY
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1810 Erie Blvd E, Near Eastside Syracuse, Syracuse, NYSpace Type
- Office
For Lease- $14.00/SF/YR
1 space available / 4,200 SF -
231-251 Cortland Ave, Southwest Syracuse, Syracuse, NYSpace Type
- Industrial
For Lease- $15.50/SF/YR
1 space available / 18,338 SF -
400 South Salina Street, Downtown Syracuse, Syracuse, NY
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405 Taylor Street West, Southwest Syracuse, Syracuse, NYSpace Type
- Industrial
For Lease- $5.00/SF/YR
1 space available / 17,250 SF -
351 South Warren Street, Syracuse, NYSpace Type
- Private Offices
For Lease-
From $500/month
Space for 1 to 5 people -
466 Salina St N, Downtown Syracuse, Syracuse, NY