Saint Louis, MO Commercial Real Estate for Lease

Search 230 commercial real estate listings for lease in Saint Louis, MO, including the latest local availabilites across all property types and find helpful local stats in the Market Overview section below.

Gravois Plaza

3843 Gravois Avenue, Tower Grove South, St. Louis, MO
Property

Retail

129,093 SF
Availability

10 Spaces

43,966 SF
Year Built

2002
For Lease Contact for pricing
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31-35 Produce Row

31-35 Produce Row, Near North Riverfront, St. Louis, MO
Property

Industrial

269,920 SF
Availability

1 Space

9,000 SF
For Lease

$13.50/SF/YR
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210 N. 17th St.

210 N. 17th St., Downtown West Saint Louis, St. Louis, MO
Property

Office

1,100 SF
Availability

1 Space

1,100 SF
For Lease

$12.00/SF/YR
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Loughborough Plaza

4324 Loughborough Avenue, Boulevard Heights, St. Louis, MO
Property

Retail

25,795 SF
Availability

1 Space

1,920 SF
For Lease Contact for pricing
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5739 Natural Bridge Avenue

5739 Natural Bridge Avenue, Mark Twain - I-70 Industrial, St. Louis, MO
Property

Industrial

118,000 SF
Availability

1 Space

118,000 SF
For Lease

$2.75/SF/YR
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BioGenerator
BioGenerator
4340 Duncan Avenue, St. Louis, MO
Services

Meeting Room

Private Office
Amenities

Kitchen

Lab space

Office supplies

Printer
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5420 & 5426 Brown Ave

5420 & 5426 Brown Ave, Mark Twain - I-70 Industrial, St. Louis, MO
Property

VacantLand

6.64 Acre
Availability

1 Space

6.64 Acre
For Lease

$3,500.00/MO
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River City Business Park - Building 2

8500 Reilly Avenue, Patch, St. Louis, MO
Property

Industrial

153,715 SF
Availability

1 Space

160,000 SF
Year Built

2023
For Lease Contact for pricing
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3407 South Jefferson Avenue
Nebula
3407 South Jefferson Avenue, St. Louis, MO
Services

Meeting Room

Private Office

Dedicated Desk
Amenities

24/7 security

Beer

Bike storage

Complimentary coffee & tea

Happy hour

High-speed internet

High-speed wifi

Kitchen

Lockable filing cabinets

Mail services
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2600 Samuel Shepard Dr.

2600 Samuel Shepard Dr., Midtown Saint Louis, St. Louis, MO
Property

Industrial

75,000 SF
Availability

1 Space

75,000 SF
For Lease

$4.25/SF/YR
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Commercial Real Estate Listings for Lease in Saint Louis, MO

The Saint Louis real estate market has a lot to offer. You will find that Industrial accounts for the largest share of CRE for lease opportunities on the local market. Meanwhile, Office accounts for the second-largest share of local listings for rent.

Saint Louis, MO Commercial Real Estate Listings for Rent

Type No. of Listings Space Available

Retail 79 791,548 Sq. Ft.

Office 77 2,485,725 Sq. Ft.

Industrial 42 2,574,746 Sq. Ft.

CRE for Rent in Saint Louis, MO by Use Type

Office

42.48%

Retail

13.53%

Industrial

44.00%

Top Locations for Commercial Space for Lease in Saint Louis, MO

Depending on the type of space that you’re looking for, different areas of Saint Louis may suit your needs differently. The city’s Downtown Saint Louis neighborhood has the highest concentration of CRE listings for lease, offering 200 availabilities on the market. The Downtown West Saint Louis neighborhood is home to the second-largest number of leasing opportunities — 33 listing(s).

At the same time, it is worth noting that the concentration of one particular type of commercial real estate in an area is a good indication of the potential of that neighborhood or submarket. For example, if you want to rent an office, consider that you will find the largest concentration of opportunities in Downtown Saint Louis.

Top Locations for CRE Listings in Saint Louis, MO

Neighborhood with most CRE Listings No. of Spaces

Downtown Saint Louis 200

Downtown West Saint Louis 33

Central West End Saint Louis 26

Top Locations for Office Listings in Saint Louis, MO

Neighborhood with most Office Listings No. of Spaces

Downtown Saint Louis 163

Downtown West Saint Louis 19

Forest Park South East 17

Areas with numerous industrial properties are also more likely to be well-connected logistically. The North Riverfront area is the local Saint Louis submarket with the most listings for rent, at this time.

Retail properties can be both scattered and clustered, mostly depending on the use type and where the location best fits in order to be close to the customers. In Saint Louis, you’ll find the most such opportunities for lease to be in Downtown Saint Louis.

Top Locations for Industrial Listings in Saint Louis, MO

Neighborhood with most Industrial Listings No. of Spaces

North Riverfront 7

Midtown Saint Louis 6

Dutchtown 4

Top Locations for Retail Listings in Saint Louis, MO

Neighborhood with most Retail Listings No. of Spaces

Downtown Saint Louis 30

Tower Grove South 18

Central West End Saint Louis 12

Mixed-Use and Green Commercial Real Estate in Saint Louis, MO

Mixed-use properties incorporate at least two different types of commercial real estate, which can present a series of advantages. The different real estate types in a mixed-use property can complement each other in ways that sustain mutual success. For instance, ground-floor retail spaces may benefit from the constant stream of office workers to and from the upper floors of the same building, as well as serve the surrounding community.

Moreover, they are in line with relatively recent trends toward a healthier, more walkable urban environment, where more amenities are placed within easier reach of the population. Properties that are built and designed with sustainability in mind provide more value for investors, while also cutting down on costs for tenants. LEED certifications attest to a property’s commitment to green building, sustainability, and lasting value. The local market includes 1 LEED-certified commercial building(s).

Distribution of LEED-Certified CRE Properties in Saint Louis, MO

LEED Silver

Recent Commercial Real Estate News

St. Louis Power Center Changes Hands

The property traded in a 1031 exchange.

Sealy Signs 1.6 MSF Renewal Near St. Louis

A long-term tenant fully occupies two industrial buildings in this suburb.

Lincoln JV Lands Refi for St. Louis Office Tower

Old National Bank provided the note, which is due to mature in 2027.

CBRE Tapped to Lease Major Part of $1.2B St. Louis Mixed-Use District

During Phase 1, developers will repurpose former industrial space for office use.

Latch Moves From NYC With 48 KSF St. Louis Lease

The relocation brings many of the company’s operations under one roof.

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Saint Louis, MO Commercial Real Estate for Lease

Gravois Plaza

31-35 Produce Row

210 N. 17th St.

Loughborough Plaza

5739 Natural Bridge Avenue

BioGenerator

5420 & 5426 Brown Ave

River City Business Park - Building 2

3407 South Jefferson Avenue

2600 Samuel Shepard Dr.