Lee County, FL Commercial Real Estate for Lease
Search 434 commercial real estate listing(s) for lease in Lee County, FL, including the latest local availabilities across all property types and find helpful local stats in the Market Overview section below.
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Alico Road & Oriole Road, Southwest Florida Airport, Fort Myers, FL
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3300 Forum Blvd, Forum, Fort Myers, FL
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4160-4224 Cleveland Avenue, Palm Lee, Fort Myers, FL
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SR 31 & Saw Palmetto Parkway, Alva, Babcock Ranch, FL
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Looking for more specific results? Choose your preferred property type

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4606 South Cleveland Avenue, Palm Lee, Fort Myers, FLSpace Type
- Retail
For Lease- $10.00/SF/YR
1 space available / 45,089 SF -
19050 Corkscrew Road, Old Corkscrew, Estero, FL
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1606 Santa Barbara Blvd, Trafalgar, Cape Coral, FLSpace Type
- Office
For Lease- $35.00/SF/YR
1 space available / 2,684 SF -
10420 Airkraft CT, Southwest Florida Airport, Fort Myers, FL
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1830 Del Prado Blvd S, Hancock, Cape Coral, FL
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10080 Intercom Dr, Southwest Florida Airport, Fort Myers, FLSpace Type
- Industrial
For Lease- $15.00/SF/YR
3 spaces available / 2,200 SF -
4600 Summerlin Road, Palm Lee, Fort Myers, FL
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3401 Bonita Beach Road, Bonita Springs, FLSpace Type
- Retail
For Lease- $15.00/SF/YR
1 space available / 861 SF -
5216 Summerlin Commons Boulevard, Fort Myers, FL
Remote Workspace and Reading Lounge - 5216 Summerlin Commons Boulevard
Remote Workspace and Reading Lounge -
13550 Intrepid Ln, Southwest Florida Airport, Fort Myers, FLSpace Type
- Land
For Lease- $8,333.33/MO
1 space available / 74,923 SF -
2407 Periwinkle Way, Sanibel, FLSpace Type
- Retail
For Lease- $25.00 - $35.00/SF/YR
2 spaces available / 843 - 2,214 SF -
2931 Michigan Ave, Dunbar, Fort Myers, FLSpace Type
- Land
For Lease- $5,500.00/MO
1 space available / 43,560 SF -
17595 S Tamiami Trl, San Carlos Park, Fort Myers, FLSpace Type
- Office
For Lease- $0.04 - $25,000.04/SF/YR
20 spaces available / 1 - 1,000 SF -
15740 New Hampshire CT, Estero Bay Park, Fort Myers, FLSpace Type
- Office
For Lease- $19.75/SF/YR
1 space available / 2,400 SF -
3210 Cleveland Ave, Sunset - Edison, Fort Myers, FL
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16140 Lee Rd, Fort Myers, FL 33912, Fiddlesticks, Fort Myers, FLSpace Type
- Industrial
For Lease- $14.00/SF/YR
2 spaces available / 11,200 - 20,160 SF -
Verdana Village Boulevard, Old Corkscrew, Estero, FL
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13351-13361 Saddle Road, Southwest Florida Airport, Fort Myers, FLSpace Type
- Industrial
For Lease- $13.00/SF/YR
1 space available / 4,876 SF -
14621 6 Mile Cypress Pkwy, Estero Bay Park, Fort Myers, FL
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3520 Old Metro Pkwy, Winkler, Fort Myers, FLSpace Type
- Industrial
For Lease- $10.75/SF/YR
1 space available / 22,451 SF -
13778 Plantation Road, Villas, Fort Myers, FL
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11521 South Cleveland Avenue, Page Park, Fort Myers, FL
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1591 HAYLEY LN, Palm Lee, Fort Myers, FLSpace Type
- Office
For Lease- $12.00/SF/YR
1 space available / 4,250 SF -
7130 College Pkwy, Villas, Fort Myers, FLSpace Type
- Office
For Lease- $22.50/SF/YR
1 space available / 2,340 SF -
1243-1306 SW Santa Barbara Blvd, Trafalgar, Cape Coral, FLSpace Type
- Retail
For Lease- $18.00/SF/YR
2 spaces available / 1,100 - 1,120 SF -
3150 Old Metro Pkwy, Winkler, Fort Myers, FLSpace Type
- Industrial
For Lease- $12.50/SF/YR
1 space available / 11,632 SF -
7997 Mercantile St Unit 8, North Fort Myers, FLSpace Type
- Office
For Lease- $15.50/SF/YR
1 space available / 2,400 SF -
20321 Summerlin Road, Sanibel View Condo, Fort Myers, FL