Lee County, FL Commercial Real Estate for Lease
Search 443 commercial real estate listing(s) for lease in Lee County, FL, including the latest local availabilities across all property types.
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3621 Cleveland Ave, Winkler, Fort Myers, FL
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5661 Independence Cir, Villas, Fort Myers, FLSpace Type
- Industrial
For Lease- $17.50 - $22.00/SF/YR
1 space available / 5,800 SF -
18070 South Tamiami Trail #11, Fort Myers, FLSpace Type
- Private Offices
For Lease-
From $650/month
Space for 1 to 3 people -
2364 Diplomat Pkwy E, Diplomat, Cape Coral, FL
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Looking for more specific results? Choose your preferred property type

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Alico Road & Oriole Road, Southwest Florida Airport, Fort Myers, FL
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5995 South Pointe Blvd, McGregor, Fort Myers, FLSpace Type
- Retail
For Lease- $25.00/SF/YR
1 space available / 3,240 SF -
7051 Cypress Terrace, Villas, Fort Myers, FLSpace Type
- Retail
For Lease- $23.00/SF/YR
3 spaces available / 2,000 - 3,458 SF -
5216 Summerlin Commons Boulevard, Fort Myers, FL
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1528-1530 Periwinkle Way, Sanibel, FLSpace Type
- Office
For Lease- $30.00/SF/YR
1 space available / 1,125 SF -
16171 San Carlos Blvd, Iona, Fort Myers, FLSpace Type
- Industrial
For Lease- $19.00/SF/YR
1 space available / 2,500 SF -
2996 Hanson St, Winkler, Fort Myers, FLSpace Type
- Industrial
For Lease- $11.50/SF/YR
1 space available / 130,143 SF -
4301 Sanibel Captiva Road, Sanibel, FL
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2765 Fowler St, Dunbar, Fort Myers, FLSpace Type
- Industrial
For Lease- $15.00/SF/YR
1 space available / 23,682 SF -
12270 Itec Park Dr, Southwest Florida Airport, Fort Myers, FLSpace Type
- Industrial
For Lease- $16.00/SF/YR
1 space available / 15,470 SF -
2075 West First Street, Sunset - Edison, Fort Myers, FLSpace Type
- Office
For Lease- $25.00/SF/YR
1 space available / 6,000 SF -
5100 South Cleveland Avenue, Palm Lee, Fort Myers, FL
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16500 Oriole Road, Fiddlesticks, Fort Myers, FL
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1261 NE 8th St, Diplomat, Cape Coral, FLSpace Type
- Industrial
For Lease- $25.00/SF/YR
1 space available / 10,056 SF -
12900 Trade Way Four, Bonita Springs, FLSpace Type
- Retail
For Lease- $25.00/SF/YR
1 space available / 1,400 SF -
2500 - 2540 NE Pine Island Rd, North Fort Myers, FLSpace Type
- Retail
For Lease- $40.00/SF/YR
1 space available / 3,700 SF -
3501 Vandenberg Way, Marsh Landing, Estero, FL
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3401 Bonita Beach Road, Bonita Springs, FLSpace Type
- Retail
For Lease- $15.00/SF/YR
1 space available / 861 SF -
17651 San Carlos Blvd, Palm Isles, Fort Myers Beach, FL
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2931 Michigan Ave, Dunbar, Fort Myers, FLSpace Type
- Land
For Lease- $5,500.00/MO
1 space available / 43,560 SF -
6700 Bayshore Road, North Fort Myers, FL
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9401 Corkscrew Palms Circle, Estero Town Center, Estero, FLSpace Type
- Office
For Lease- $21.00/SF/YR
1 space available / 2,907 SF -
434 NE 3rd Ave, Diplomat, Cape Coral, FL
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4301 Sanibel Captiva Rd, Sanibel, FL
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15675 McGregor Blvd, Iona, Fort Myers, FL
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11637 Kelly Rd., Iona, Fort Myers, FLSpace Type
- Industrial
For Lease- $17.00/SF/YR
2 spaces available / 1,500 SF -
N. Cleveland Avenue, Palmona Park, North Fort Myers, FL
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4383 Colonial Blvd, Omni - Heritage Palms, Fort Myers, FLSpace Type
- Retail
For Lease- $25.00/SF/YR
3 spaces available / 940 - 3,000 SF