US Hwy 281 & Encino Rio

For Lease

19818 US-281, San Antonio, TX 78258

The total number of office spaces available at US Hwy 281 & Encino Rio is 1. Leasing opportunities in the building include medical office. There is a total of 44,859 square feet of space currently available for rent at this address. Of this, the minimum divisible area is 2,500 square feet.

Space Available For Lease 1

Contacts

David Held

Endura Advisory Group

Property Details

  • Property Type Office - Medical Office
  • Property Size 44,859 SF
  • Lot Size 9.32 Acre
  • Date Updated May 14, 2026

±9.32 Acres (Divisible) | Hwy 281 & Encino Rio

- Highly visible location

- Development ready

- Impervious Cover - Category 2

- Excellent ingress & egress

- 5-mile trade area has experienced a strong annual growth over the last 5 years and is projected to continue growing.

Want more info on this listing?

Reach out to the broker for more info on lease terms and amenities

Getting around

  • 12/100

    Walk Score ®

  • 20/100

    Transit Score ®

  • 27/100

    Bike Score ®

Powered by Walk Score ®

Location

  • City San Antonio, TX
  • Neighborhood Encino Park
  • Zip Code 78258
  • Market San Antonio

Points of Interest

  • Longhorn and Western Train Platform

    5.67 miles

  • Wonderland Express Train Station

    7.29 miles

  • Spassburg Train Station

    9.27 miles

  • Crackaxle Train Station

    9.47 miles

  • Chevron

    2.18 miles

  • Valero

    2.37 miles

  • H-E-B Fuel

    3.26 miles

  • Shell

    3.88 miles

  • Ten-o-Five Market

    4.26 miles

  • Tesla Supercharger

    9.09 miles

  • Mud Creek Park Parking

    2.67 miles

  • Sky Plaza Parking

    6.22 miles

  • Big Brother and Big Sister Parking

    6.24 miles

  • Employee parking

    6.63 miles

  • Short Term Parking & Car Rental

    7.01 miles

  • Oversized Vehicle Parking

    7.05 miles

  • Long Term Parking

    7.07 miles

  • Orange Lot

    7.27 miles

  • Green Lot

    7.28 miles

  • Rideshare Waiting Lot

    7.39 miles

  • Holiday Inn

    0.37 miles

  • Courtyard

    0.92 miles

  • Candlewood Suites

    0.93 miles

  • Hyatt Place

    1.09 miles

  • Best Western Plus Hill Country Suites

    1.15 miles

  • Home2 Suites by Hilton San Antonio North Stone Oak

    1.21 miles

  • Residence Inn San Antonio North Stone Oak

    1.46 miles

  • Comfort Suites San Antonio North - Stone Oak

    1.50 miles

  • Fairfield Inn & Suites San Antonio North/Stone Oak

    1.52 miles

  • Hampton Inn

    1.52 miles

  • H-E-B Plus!

    0.99 miles

  • Walmart Supercenter

    1.20 miles

  • Burlington

    1.21 miles

  • H-E-B

    1.44 miles

  • Marshalls

    1.45 miles

  • Target

    2.05 miles

  • Sprouts Farmers Market

    2.33 miles

  • Big Lots

    2.34 miles

  • Trader Joe's

    2.68 miles

  • Buff City Soap

    3.25 miles

19818 US-281 Listing Brief

  • Leasing rates here can depend on a variety of factors, including the quality rating of the property (property class or building class), the position of the available space within the building, any unique attributes that the listed space may include, as well as on the availability of on-site or nearby amenities. Reach out using the contact form available on this page to schedule a tour or to get more detailed information on the most modern facilities and amenities that 19818 US-281 has to offer.

  • See the listing area details for information and ratings regarding the degree of walkability in the neighborhood, the accessibility and frequency of public transit options, as well as the level of availability and quality of biking infrastructure in the area. What’s more, you can use the interactive map for a good overview of the area. Location details also include a breakdown of distance from the property to several essential amenities and points of interest, which may include parking facilities, fuel stations, stores, or hotels.

  • This property is in the Encino Park neighborhood of San Antonio and located within zip code 78258.

    The building includes 44,859 square feet, of which 44,859 square feet is rentable office space.

Contact Listing Broker
  1. 1Main information
  2. 2Extra information
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