3875 E Southcross Blvd

For Lease

3875 E Southcross Blvd, San Antonio, TX 78222

There are currently 5 spaces available at this property. This building incorporates a total of 20,405 square feet. Of that, 7,804 square feet is rentable space. The general use of the property is designated as mixed use. Units available for lease at 3875 E Southcross Blvd include spaces that are described as office / retail / medical.
Current availabilities are located on multiple floors in the building. The largest available space at this property is 2,045 square feet. Listed spaces in this building start at a size of 765 square feet.
See more information under each individual listing below for additional details, such as divisible space, renewal options, lease type, possibility of sublease and more.

Space Available For Lease 5

Contacts

Allen Niesinov

DH Realty Partners

Property Details

  • Property Type Mixed Use - Office / Retail / Medical
  • Property Size 20,405 SF
  • Lot Size 0.92 Acre
  • Zoning C-2, O-2
  • Property Tenancy Multi-Tenant
  • Year Built 1981
  • Date Updated Mar 1, 2026

Situated within a well-established medical corridor, this property offers an excellent opportunity for medical, wellness, and professional users seeking proximity to a strong patient base. The center benefits from high daily traffic driven by surrounding medical offices and healthcare facilities. Suites are available in a variety of sizes and are in turnkey condition, allowing tenants to occupy and begin operations with minimal build-out. The property is well-suited for practices and service providers looking to capitalize on consistent patient demand in a proven medical market.

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Reach out to the broker for more info on lease terms and amenities

Highlights

  • Turnkey Offices
  • Flexible suite sizes available
  • Affordable, high-exposure location
  • Ideal for retail, medical, and neighborhood service tenants

Attachments

Getting around

  • 26/100

    Walk Score ®

  • 37/100

    Transit Score ®

  • 37/100

    Bike Score ®

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Location

  • City San Antonio, TX
  • Neighborhood Pecan Valley
  • Zip Code 78222
  • Market San Antonio

Points of Interest

  • San Antonio

    4.72 miles

  • San Antonio Zoo Eagle Train Station

    6.81 miles

  • Valero

    0.83 miles

  • Diamond Shamrock

    1.29 miles

  • Goliad Express Citgo

    1.51 miles

  • Shell

    1.54 miles

  • Exxon

    1.75 miles

  • H-E-B Fuel

    1.76 miles

  • ChargePoint Charging Station

    2.94 miles

  • ChargePoint

    5.79 miles

  • Tesla Supercharger

    9.92 miles

  • Staff Parking

    1.87 miles

  • Salado Creek Greenway Parking

    2.34 miles

  • H-E-B plus! Curbside Parking

    2.44 miles

  • Lot 3

    3.68 miles

  • Lot 2

    3.71 miles

  • Lot 1

    3.75 miles

  • Lot 4

    3.80 miles

  • Media Lot

    3.82 miles

  • Lot 5

    3.99 miles

  • Lot 6

    4.01 miles

  • Brookside Inn

    1.57 miles

  • Pecan Valley Inn

    1.59 miles

  • Quality Inn & Suites

    1.61 miles

  • La Quinta Inn

    1.83 miles

  • Fairfield Inn & Suites

    1.83 miles

  • Holiday Inn Express & Suites

    2.06 miles

  • Hampton Inn & Suites

    2.11 miles

  • Motel 6

    2.16 miles

  • Super 8

    2.20 miles

  • Days Inn

    2.21 miles

  • La Fiesta

    1.43 miles

  • La Michoacana Meat Market

    1.55 miles

  • JC Food Mart

    1.57 miles

  • H-E-B

    1.75 miles

  • Target

    1.82 miles

  • Walmart Supercenter

    2.09 miles

  • H-E-B plus!

    2.41 miles

  • Marshalls

    2.45 miles

  • Burlington

    2.49 miles

  • Macy's

    5.18 miles

Contact Listing Broker
Allen Niesinov

DH Realty Partners

  1. 1Main information
  2. 2Extra information
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