116-122 South Main Street

For Lease

116-122 South Main Street, Woodruff, SC 29388

You can currently find 1 retail space(s) available for lease at 116-122 South Main Street. Designated use type for space listed here includes street retail. Current retail listings at this property total 14,400 square feet. Lease type options include NNN. Expand the listing and property details below for additional information on leasing opportunities at 116-122 South Main Street.

Space Available For Lease 1

Contacts

Brett Mitchell

SVN | Palmetto

Property Details

  • Property Type Retail - Street Retail
  • Property Size 14,400 SF
  • Lot Size 0.49 Acre
  • Date Updated Sep 18, 2026
116–122 S Main Street is positioned in the heart of Downtown Woodruff, where historic character, new investment, and rapid residential growth are converging. Surrounded by the activity of Main Street and minutes from new retail, hospitality, and neighborhood development, the property offers a highly visible downtown address for a tenant seeking to become a true anchor in one of the Upstate’s most compelling growth markets.116–122 S Main Street presents a rare opportunity to lease a large-format, anchor-style commercial property in the heart of Downtown Woodruff, South Carolina. The property offers approximately ±14,400 SF of available space and has been stripped down to a clean, buildout-ready condition, creating exceptional flexibility for a tenant seeking a customized downtown presence. Ownership’s preferred vision is to secure a qualified national, credit, or strong regional tenant capable of occupying the full footprint and creating a true destination anchor for Downtown Woodruff. The size, visibility, architectural character, and Main Street positioning of the property make it well-suited for a specialty retailer, lifestyle concept, market-style operator, food and beverage anchor, experiential retail user, or other high-quality tenant that can help drive traffic and elevate the surrounding downtown district. While a single full-building tenant is the preferred strategy, ownership remains flexible and will consider subdividing the property into smaller footprints for the right tenant mix. The building can support a variety of potential configurations, including single-tenant occupancy, dual-tenant layouts, creative multi-tenant concepts, restaurant/retail combinations, or adaptive reuse strategies that activate both the main level and upper level. This is not a standard lease opportunity. It is a chance for the right tenant to become a defining anchor in one of the Upstate’s most active emerging downtown markets and play a meaningful role in the continued growth and revitalization of Woodruff, SC.
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Highlights

  • ±14,400 SF available, subject to final verification
  • Buildout-ready shell condition with creative delivery options available
  • Flexible layout allows for single-tenant, dual-tenant, or multi-tenant concepts
  • Ideal for specialty retail, lifestyle, food & beverage, market, experiential, or hybrid concepts
  • Large-format, anchor-style Main Street opportunity
  • Opportunity to help define the next chapter of Downtown Woodruff
  • Prime position in the heart of Downtown Woodruff seeing ±22,100 ADV
  • Seeking qualified national, credit, or strong regional tenant

Getting around

  • 46/100

    Walk Score ®

  • 44/100

    Bike Score ®

Powered by Walk Score ®

Location

  • City Woodruff, SC
  • Neighborhood Woodruff
  • Zip Code 29388
  • Market Greenville

Points of Interest

  • Marathon

    0.20 miles

  • Exxon

    0.74 miles

  • Lucky

    4.50 miles

  • Shell

    6.27 miles

  • Citgo

    7.50 miles

  • Truck Stop

    7.97 miles

  • Shell Gasoline

    8.05 miles

  • Trail Access Parking

    9.15 miles

  • Staff/Visitor Parking

    9.33 miles

  • Center Parking

    9.96 miles

  • Tap Three

    0.03 miles

  • Claudio's Bistro

    0.06 miles

  • Burger King

    0.12 miles

  • Zaxby's

    0.25 miles

  • Bronco Mexican Retaurant

    0.31 miles

  • Friends Cafe

    0.33 miles

  • Pizza Hut

    0.56 miles

  • Demeter's

    0.58 miles

  • Carolina Fine Foods

    0.60 miles

  • Subway

    0.63 miles

  • Food Lion

    1.05 miles

  • Dollar General Market

    9.66 miles

116-122 South Main Street Listing Brief

  • A property’s location contributes to the asking rent almost as much as its characteristics do. For instance, central urban locations with high walkability or suburban locations with ample parking and easy access by car will claim higher rents but offer superior access to your customer base. Likewise, the quality of the building systems and property finishes have a significant impact on how businesses can conduct their activity there, as well as on the experience of their customers.

    The rent for retail space at 116-122 South Main Street is available upon request. Feel free to reach out using the contact form conveniently included on this page to find out more about what the property can offer for your business.

  • The property includes 14,400 square feet of retail space for lease. Of this total, 14,400 square feet are Street Retail.

    Lease agreement conditions for the availability at this property include NNN.

    For more information or to schedule a tour of the property, use the convenient contact form on this page to get in touch with a representative.

  • You should keep in mind that different areas gradually build a reputation as hotspots or desirable corridors for shopping, eating, or other entertainment and consumer activities. So, while renting retail space in an area with a well-established high-end reputation might mean more customers that are more willing to spend, it will also place you in a more competitive environment.

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