For Sale: ±102-Acre Mixed-Use Development Opportunity | Orangeburg, SC

For Sale

Hwy 601 St Matthews Road, Orangeburg, SC

This Orangeburg property for sale is located at Hwy 601 St Matthews Road. Contact the listing broker for details on the current sale price for For Sale: ±102-Acre Mixed-Use Development Opportunity | Orangeburg, SC. For Sale: ±102-Acre Mixed-Use Development Opportunity | Orangeburg, SC is situated on a lot that is 101 square feet in size.

Contacts

John Gressette

Property Details

  • Property Type Other
  • Lot Size 101 SF
  • Date Updated Jun 30, 2026

Opportunity
This ±102‑acre mixed-use development site in Orangeburg, South Carolina, offers a versatile opportunity for residential, retail and commercial development within one of the market’s active corridors. Featuring strong frontage on Hwy 601 (St. Matthews Road) and on‑site utilities, the proposed site plan includes residential acreage, big‑box retail, outparcels, office/neighborhood commercial parcels and a convenience store pad. Its proximity to major employers, educational institutions and expanding industrial operations enhances long-term demand drivers, making it an attractive investment for developers seeking opportunities in a growing regional market.

Location
The St. Matthews Road corridor in Orangeburg, SC, presents a highly attractive market for retail property buyers thanks to its strategic location and robust commercial activity. The area benefits from easy access to I‑26 Exit 145 (±55,200 VPD), nearby Orangeburg-Calhoun Technical College and MUSC Health, creating a built-in customer base. Currently zoned as General Commercial, this property is located within a growing business corridor supported by established retail, healthcare, and financial services, making it a strong development opportunity in Orangeburg.

For more information, download the flyer and contact the listing broker, John Gressette.

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Getting around

  • 14/100

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  • 28/100

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Location

  • City Orangeburg, SC

Points of Interest

  • Kwik Stop

    0.18 miles

  • Shell

    1.29 miles

  • Sunoco

    1.34 miles

  • Exxon

    1.51 miles

  • BP

    1.53 miles

  • Marathon

    2.05 miles

  • Citgo

    2.09 miles

  • Murphy USA

    3.18 miles

  • Teacher Parking Lot

    3.11 miles

  • Student Parking Lot

    3.19 miles

  • Baymont Orangeburg North

    1.21 miles

  • Super 8

    1.30 miles

  • Southern Lodge

    1.33 miles

  • Travelodge

    1.36 miles

  • Suburban Studios

    1.42 miles

  • Quality Inn & Suites

    1.42 miles

  • Hampton

    1.44 miles

  • Days Inn

    1.50 miles

  • Sleep Inn

    1.52 miles

  • Country Inn & Suites

    1.57 miles

  • Piggly Wiggly

    2.08 miles

  • Lidl

    2.94 miles

  • ALDI

    3.04 miles

  • TJ Maxx

    3.26 miles

  • Walmart Supercenter

    3.31 miles

  • Walmart Neighborhood Market

    4.14 miles

Contact Listing Broker
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