Stand Alone Medical & Office Building

For Lease

4101 Main St, Suites E & F , Hilton Head Island, SC 29926

The total number of office spaces available at Stand Alone Medical & Office Building is 3. Leasing opportunities in the building include general office, office and medical office. There is a total of 7,200 square feet of space currently available for rent at this address. Of this, the minimum divisible area is 1,286 square feet.

Space Available For Lease 3

Contacts

Baker Wilkins

NAI Carolina Charter

Property Details

  • Property Type Office - Medical Office
  • Property Size 3,600 SF
  • Lot Size 2.25 Acre
  • Building Class A
  • Year Built 2001
  • Date Updated Apr 28, 2026
Stand Alone Medical & Office Building Available on North End of Hilton HeadStand Alone Medical or Office Building for Sale or Lease on Hilton Head.Stand Alone Medical & Office Building for Lease OR Sale on Hilton Head Island
Want more info on this listing?

Reach out to the broker for more info on lease terms and amenities

Highlights

  • Recently vacated, the building is ready for immediate tenant improvements or occupancy, offering an ideal setting for medical or wellness users seeking a convenient and professional island location.
  • Suite E consists of reception/waiting area, 3-4 offices, conference room, storage and restroom.
  • Suite F consists of waiting room, nursing/business area, +/- 7 exams rooms, break room and restroom.
  • The property provides easy access to Hilton Head Hospital, the surrounding professional area, and nearby Bluffton.
  • Very attractive stand-alone medical office building located on Main Street on the north end of Hilton Head Island, just off Highway 278.

Attachments

Getting around

  • 46/100

    Walk Score ®

  • 65/100

    Bike Score ®

Powered by Walk Score ®

Location

  • City Hilton Head Island, SC
  • Zip Code 29926

Points of Interest

  • BP

    0.42 miles

  • Speedway

    1.49 miles

  • Kroger

    2.31 miles

  • Shell

    4.46 miles

  • Enmark

    4.51 miles

  • ChargePoint

    4.72 miles

  • Harris Teeter Fuel

    4.77 miles

  • Harbour Town Parking

    7.04 miles

  • Ramada Hilton Head

    0.20 miles

  • Hampton Inn Hilton Head Island

    1.77 miles

  • Marriott's SurfWatch

    2.30 miles

  • Marriott's Harbour Point and Sunset Pointe

    2.32 miles

  • Days Inn by Wyndham Hilton Head

    2.60 miles

  • Palmetto Dunes Oceanfront Resort

    2.61 miles

  • SpringHill Suites

    2.77 miles

  • Home2 Suites by Hilton Hilton Head

    2.78 miles

  • Red Roof Inn

    2.85 miles

  • Marriott's Barony Beach Club

    2.86 miles

  • Walmart Supercenter

    0.30 miles

  • Publix

    0.48 miles

  • Harris Teeter

    0.53 miles

  • Whole Foods Market

    2.10 miles

  • TJ Maxx

    2.13 miles

  • Kroger

    2.14 miles

  • Belk

    2.16 miles

  • The Fresh Market

    3.15 miles

  • Piggly Wiggly

    5.06 miles

  • Saks Fifth Avenue

    6.29 miles

4101 Main St, Suites E & F Listing Brief

  • Leasing rates here can depend on a variety of factors, including the quality rating of the property (property class or building class), the position of the available space within the building, any unique attributes that the listed space may include, as well as on the availability of on-site or nearby amenities. Reach out using the contact form available on this page to schedule a tour or to get more detailed information on the most modern facilities and amenities that 4101 Main St, Suites E & F has to offer.

  • See the listing area details for information and ratings regarding the degree of walkability in the neighborhood, the accessibility and frequency of public transit options, as well as the level of availability and quality of biking infrastructure in the area. What’s more, you can use the interactive map for a good overview of the area. Location details also include a breakdown of distance from the property to several essential amenities and points of interest, which may include parking facilities, fuel stations, stores, or hotels.

  • 4101 Main St, Suites E & F was originally completed in 2001 and is rated class A. The building includes 3,600 square feet, of which 7,200 square feet is rentable office space.

Contact Listing Broker
Baker Wilkins

NAI Carolina Charter

  1. 1Main information
  2. 2Extra information
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.