Map of Property

Two Suites Available for Lease in Office/Medical Building | Columbia

For Lease

4100 N Main St, Columbia, SC 29203

The total number of office spaces available at Two Suites Available for Lease in Office/Medical Building | Columbia is 1. Leasing opportunities in the building include general office. There is a total of 3,742 square feet of space currently available for rent at this address. Of this, the minimum divisible area is 1,226 square feet.

Space Available For Lease 1

Contacts

broker
Thomas Johnson

Colliers

broker
Mary Teaster

Colliers

Property Details

  • Property Type Office - General Office
  • Year Renovated 2019
  • Date Updated Jun 27, 2025

Located at 4100 North Main Street, these two contiguous suites are available in a two-story freestanding office building. The building was recently renovated in 2019 and sits on a large ±1.3-acre lot, providing ample parking for tenants and clients. The property is situated in the North Main (NOMA) district of Downtown Columbia. The location offers convenient access to Downtown Columbia, Prisma Health Richland Hospital, Interstate 126 and Highway 277.

Available suites for lease:

Suite 200 | ±1,226 SF
Suite 201 | ±2,516 SF
Can be combined for a total contiguous area of ±3,742 SF

For more information, please download the flyer and contact the listing brokers, Tommy Johnson or Mary Winter Teaster.

Want more info on this listing?

Reach out to the broker for more info on lease terms and amenities

Highlights

  • ±2 miles to Bull Street District
  • ±2 miles to Downtown Columbia and Prisma Health Richland Hospital
  • Generous on-site parking
  • Predominantly configured for clinical and medical uses, but can also support traditional office use
  • Property managed by Colliers

Attachments

Getting around

  • 63/100

    Walk Score ®

  • 32/100

    Transit Score ®

  • 37/100

    Bike Score ®

Powered by Walk Score ®

Location

  • City Columbia, SC
  • Neighborhood Seminary Ridge
  • Zip Code 29203
  • Market Columbia

Points of Interest

  • Columbia

    3.15 miles

  • Sunoco

    0.30 miles

  • Speedway

    0.51 miles

  • Shell

    0.84 miles

  • Marathon

    1.90 miles

  • Exxon

    1.90 miles

  • BP

    1.92 miles

  • Flying J

    1.95 miles

  • Columbia, SC Supercharger

    6.86 miles

  • Columbia, SC - Harbison Boulevard Supercharger

    7.04 miles

  • Circle K

    8.96 miles

  • Prisma Health Baptist Hospital Parking

    2.24 miles

  • P. Cannon Garage

    2.27 miles

  • Taylor Street Garage

    2.30 miles

  • Parking of CSH

    2.43 miles

  • AD7 Lot

    2.47 miles

  • Lady Street Parking Garage

    2.65 miles

  • AD12

    2.95 miles

  • B6 Lot

    3.00 miles

  • 901 Park St Garage

    3.01 miles

  • Park View Inn

    0.79 miles

  • Super 8 by Wyndham Columbia

    1.86 miles

  • Glass Manor

    1.94 miles

  • Staybridge Suites

    2.30 miles

  • Hotel Trundle

    2.31 miles

  • Columbia Marriott

    2.41 miles

  • Coronet

    2.42 miles

  • Holiday Inn Columbia - Downtown

    2.46 miles

  • Sheraton Columbia Downtown Hotel

    2.48 miles

  • Suburban Extended Stay Hotel

    2.54 miles

  • Food Lion

    1.15 miles

  • Uncle Willie's Grocery Store

    1.72 miles

  • Piggly Wiggly

    2.38 miles

  • Market Place Shopping Center

    2.82 miles

  • Publix

    2.88 miles

  • Halal International

    2.92 miles

  • Asian Market

    3.01 miles

  • Burlington

    3.03 miles

  • Dutch Square Mall

    3.10 miles

  • Kroger

    3.10 miles

4100 N Main St Listing Brief

  • Leasing rates here can depend on a variety of factors, including the quality rating of the property (property class or building class), the position of the available space within the building, any unique attributes that the listed space may include, as well as on the availability of on-site or nearby amenities. Reach out using the contact form available on this page to schedule a tour or to get more detailed information on the most modern facilities and amenities that 4100 N Main St has to offer.

  • See the listing area details for information and ratings regarding the degree of walkability in the neighborhood, the accessibility and frequency of public transit options, as well as the level of availability and quality of biking infrastructure in the area. What’s more, you can use the interactive map for a good overview of the area. Location details also include a breakdown of distance from the property to several essential amenities and points of interest, which may include parking facilities, fuel stations, stores, or hotels.

  • This property is in the Seminary Ridge neighborhood of Columbia and located within zip code 29203.

    The most recent renovation completed at this address was in 2019.

In-Depth Research Available for this Property

Access more in-depth information about this property — including ownership, tenant details, property characteristics and transaction history, along with local market insights and much more — on CommercialEdge.

Contact Two Suites Available for Lease in Office/Medical Building | Columbia
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