5321 N Main St

For Sale

5321 N Main St, Columbia, SC 29203

This Columbia property for sale is located at 5321 N Main St. The current listed sale price for 5321 N Main St is $175,000. 5321 N Main St is situated on a lot that is 0.45 acre in size.

Contacts

Sam DeWees

DeWees Real Estate

Property Details

  • Property Type Office
  • Property Size 1,305 SF
  • Lot Size 0.45 Acre
  • Year Built 1955
  • Date Updated Nov 11, 2026
  • Visibility/Traffic Count (VPD) 8,200

Office/Specialty Building at 5321 N Main St, Columbia, SC 29203 offers a rare opportunity to acquire or lease a versatile, move-in-ready property in a highly accessible Columbia location. Positioned just minutes from Downtown Columbia and I-20, this 1,305 SF heated building is ideal for office, specialty, operational services, or childcare-related users, with a former 27-child capacity already established. Situated on approximately 0.45 acres, the fully fenced site features a lockable gate, providing added security and functionality. The property also includes a covered carport and an additional 500 SF storage building with a roll-up door, creating valuable space for equipment, supplies, or operational support. Recent capital improvements enhance the property’s appeal, including new HVAC and ductwork in 2025, a roof replacement on the main building in 2021, and a new roof for the rear storage building in 2026. With visibility along N Main Street and traffic counts of approximately 8,200 vehicles per day, this site combines convenience, flexibility, and exposure at an attractive price point. Offered for sale at $175,000 or for lease at $1,350/month plus utilities. 

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Getting around

  • 54/100

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  • 33/100

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  • 36/100

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Location

  • City Columbia, SC
  • Neighborhood Belmont
  • Zip Code 29203
  • Market Columbia

Points of Interest

  • Columbia

    4.18 miles

  • Shell

    0.53 miles

  • Obama Store

    0.62 miles

  • Exxon

    0.80 miles

  • Flying J

    0.84 miles

  • Murphy USA

    1.55 miles

  • Sunoco

    1.64 miles

  • Speedway

    1.80 miles

  • Columbia, SC Supercharger

    5.50 miles

  • Columbia, SC - Harbison Boulevard Supercharger

    7.80 miles

  • Circle K

    9.54 miles

  • Prisma Health Baptist Hospital Parking

    3.18 miles

  • P. Cannon Garage

    3.23 miles

  • AD7 Lot

    3.23 miles

  • Taylor Street Garage

    3.31 miles

  • Parking of CSH

    3.39 miles

  • Lady Street Parking Garage

    3.61 miles

  • B6 Lot

    3.73 miles

  • Finlay House Parking Garage

    3.88 miles

  • AD12

    3.90 miles

  • Glass Manor

    0.59 miles

  • Super 8 by Wyndham Columbia

    0.74 miles

  • Coronet

    1.07 miles

  • Park View Inn

    2.05 miles

  • Days Inn Columbia NE Fort Jackson

    2.21 miles

  • Hotel Trundle

    3.27 miles

  • Columbia Marriott

    3.37 miles

  • Hilton Garden Inn

    3.38 miles

  • Holiday Inn Columbia - Downtown

    3.40 miles

  • Sheraton Columbia Downtown Hotel

    3.43 miles

  • Food Lion

    0.30 miles

  • Piggly Wiggly

    1.02 miles

  • Uncle Willie's Grocery Store

    2.81 miles

  • Kroger

    2.87 miles

  • Market Place Shopping Center

    3.45 miles

  • Macy's

    3.51 miles

  • Two Notch Retail

    3.56 miles

  • Burlington

    3.56 miles

  • Columbia Place Mall

    3.57 miles

  • Trader Joe's

    3.60 miles

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