Map of Property

278 E Main St

For Lease

278 E Main St, Smithtown, NY 11787

The total number of office spaces available at 278 E Main St is 4. Leasing opportunities in the building include medical office. There is a total of 4,400 square feet of space currently available for rent at this address. Of this, the minimum divisible area is 800 square feet.

Space Available For Lease 4

Contacts

Vincent Piazza

R&R Commercial Realty Group

Property Details

  • Property Type Office - Medical Office
  • Property Size 12,000 SF
  • Lot Size 0.74 Acre
  • Building Class C
  • Date Updated Mar 31, 2026
Want more info on this listing?

Reach out to the broker for more info on lease terms and amenities

Getting around

  • 53/100

    Walk Score ®

  • 50/100

    Bike Score ®

Powered by Walk Score ®

Location

  • City Smithtown, NY
  • Neighborhood Village of the Branch
  • Zip Code 11787
  • Market Long Island

Points of Interest

  • Platform A - Crossover

    0.99 miles

  • Smithtown

    1.04 miles

  • Platform B

    1.05 miles

  • Platform A

    1.05 miles

  • St. James

    2.24 miles

  • Saint James

    2.25 miles

  • Suffolk / Lowell

    4.38 miles

  • LIRR Station Parking

    4.40 miles

  • Central Islip

    4.41 miles

  • Central lslip Station Entrance

    4.42 miles

  • BP

    1.05 miles

  • Speedway

    1.86 miles

  • Mobil

    1.94 miles

  • bp

    2.41 miles

  • Cumberland Farms

    2.85 miles

  • Conoco

    3.10 miles

  • Tesla Supercharger

    3.46 miles

  • QuickChek

    3.77 miles

  • ChargePoint

    4.72 miles

  • North Parking Lot

    3.21 miles

  • South Parking Lot

    3.36 miles

  • David Weld Sanctuary Parking Lot

    3.81 miles

  • Long Island Expressway Exit 56 Park & Ride

    3.91 miles

  • South P Lot

    4.00 miles

  • Parking Lot - Dirt & Gravel Surface

    4.74 miles

  • H Lot

    4.92 miles

  • Hospital Parking Garage

    4.93 miles

  • Staff Parking Lot A

    4.96 miles

  • SAC Lot

    5.00 miles

  • Americas Best Value Inn

    0.92 miles

  • Residence Inn Long Island Hauppauge/Islandia

    2.75 miles

  • Hyatt Regency Long Island

    2.77 miles

  • The Smithtown Inn

    3.11 miles

  • Hampton Inn

    3.28 miles

  • Holiday Inn Express

    3.94 miles

  • 1129

    4.47 miles

  • The Stony Brookside Bed & Bike Inn

    4.50 miles

  • Estate at Three Village Inn

    4.73 miles

  • Olympic Motor Lodge

    4.80 miles

  • Uncle Giuseppe's

    0.37 miles

  • Stop & Shop

    1.42 miles

  • Giunta's Meat Farms

    1.45 miles

  • Hauppauge Shopping Centre

    2.22 miles

  • ShopRite

    2.31 miles

  • St. James General Store

    2.45 miles

  • Smith Haven Mall

    2.51 miles

  • ALDI

    2.54 miles

  • Bob's Discount Furniture

    2.62 miles

  • Macy's

    2.78 miles

278 E Main St Listing Brief

  • Leasing rates here can depend on a variety of factors, including the quality rating of the property (property class or building class), the position of the available space within the building, any unique attributes that the listed space may include, as well as on the availability of on-site or nearby amenities. Reach out using the contact form available on this page to schedule a tour or to get more detailed information on the most modern facilities and amenities that 278 E Main St has to offer.

  • See the listing area details for information and ratings regarding the degree of walkability in the neighborhood, the accessibility and frequency of public transit options, as well as the level of availability and quality of biking infrastructure in the area. What’s more, you can use the interactive map for a good overview of the area. Location details also include a breakdown of distance from the property to several essential amenities and points of interest, which may include parking facilities, fuel stations, stores, or hotels.

  • This property is in the Village of the Branch neighborhood of Smithtown and located within zip code 11787.

    278 E Main St is rated class C. The building includes 12,000 square feet, of which 4,400 square feet is rentable office space.

Contact Listing Broker
Vincent Piazza

R&R Commercial Realty Group

  1. 1Main information
  2. 2Extra information
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.