208 E 75th St

For Lease

208 E 75th St, New York, NY 10021

There is currently one space available at 208 E 75th St. The building’s general use is multi-family. The space listed for lease is described as medical office. Current availability totals 900 square feet. Of this, minimum divisible area is 900 square feet. The listed lease rate is $5,500.00/MO. The lease term is from 1 to 10 years and the lease type is Modified Gross. The build type offered for this lease is partial build out.

Space Available For Lease 1

Contacts

Alexandru Galiceanu

Lexington Real Estate Group

Principal Broker

Property Details

  • Property Type Multi-Family
  • Property Size 5,300 SF
  • Units 4
  • Lot Size 0.05 Acre
  • Zoning R8B
  • # of Floors 5
  • Average Floor Size 950 SF
  • Property Tenancy Single Tenant
  • Building Class B
  • Year Built 1910
  • Year Renovated 2026
  • Date Updated Jul 13, 2026

Prime Upper East Side Maisonette Medical/Professional Suite 

 

Situated in the heart of Manhattan’s prestigious Lenox Hill neighborhood, 208 East 75th Street offers an exceptional, high-visibility opportunity for healthcare practitioners, wellness professionals, and non-profit institutions. Occupying the garden level of a beautiful, boutique 5-story townhouse, this turnkey commercial space features a dedicated private entrance just a few steps below street level, offering an ideal balance of street-level accessibility and user privacy.

 

The entire ground floor has undergone a complete, high-end renovation, boasting premium wood flooring, sleek recessed LED lighting, a newly updated bathroom, and fully modernized electrical systems throughout. The property currently sits as a pristine, expansive open-concept layout with a private room positioned at the rear, offering an immediate blank canvas that requires zero structural work for open-plan tenants, while remaining highly adaptable for clinical division.

 

Versatile Layout Potential: Immediate Turnkey Open Concept or Seamless Medical Build-Out

 

For practices requiring a traditional multi-room clinical environment, the generous footprint easily configures into a highly efficient, multi-operatory floor plan. The space can seamlessly accommodate:

- A spacious, welcoming patient reception and check-in lobby directly off the entryway foyer.

- A dedicated administrative and billing hub with an integrated communication window.

- Multiple private examination rooms or clinical operatories.

- A separate, expansive doctor’s executive consultation suite.

- A staff kitchen/break area and localized storage hubs.

 

The property's flexible layout and Group 3 zoning make it ideal for a wide variety of professional organizations, including:

 

Medical & Clinical Practices: Perfect for private medical practices, dental clinics, dermatology, and multi-provider medical groups.

Outpatient & Wellness Centers: Exceptionally well-suited for sports physical therapy, chiropractic care, acupuncture collectives, and holistic health centers that benefit from the open-concept layout.

Private Consultation & Mental Health Suites: Ideal for psychiatrists, psychologists, speech therapists, and counselors seeking a highly private, quiet, and discreet environment with a dedicated street entrance.

Creative & Cultural Non-Profit Foundations: The pristine open layout is a flawless match for 501(c)(3) non-commercial art galleries, foundations, literary societies, historical archives, or boutique reading rooms.

Educational & Philanthropic Institutions: Highly adaptable for boutique specialized schools, STEM learning labs, private tutoring networks, or administrative headquarters for philanthropic organizations.

 

Located in one of Manhattan’s most pedestrian-friendly and affluent residential enclaves, your space is surrounded by premium retail, fine dining, and neighborhood amenities. Transit options are exceptionally convenient for both staff and clients, with immediate access to Third and Lexington Avenue subway lines (Q and 6 trains) and cross-town bus routes.

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Attachments

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Location

  • City New York, NY
  • Neighborhood Lenox Hill
  • Zip Code 10021
  • Market Manhattan

Points of Interest

  • 72nd Street & 2nd Avenue at Northwest Corner

    0.16 miles

  • East 77th Street & Lexington Avenue at Southeast Corner

    0.17 miles

  • East 77th Street & Lexington Avenue at Northeast Corner

    0.17 miles

  • 77th Street

    0.18 miles

  • East 77th Street & Lexington Avenue at Southwest Corner

    0.18 miles

  • East 77th Street & Lexington Avenue at Northwest Corner

    0.19 miles

  • 72nd Street & 2nd Avenue at Southeast Corner

    0.19 miles

  • East 68th Street & Lexington Avenue at Northeast Corner

    0.36 miles

  • East 68th Street & Lexington Avenue at Northwest Corner

    0.36 miles

  • 68th Street–Hunter College

    0.37 miles

  • ChargePoint

    0.27 miles

  • plugNYC

    0.82 miles

  • Shell

    1.08 miles

  • BP

    1.38 miles

  • Citgo

    1.38 miles

  • Atlantic

    1.43 miles

  • Mobil

    1.48 miles

  • Sunoco

    1.52 miles

  • iClean

    0.12 miles

  • Surrey Garage

    0.36 miles

  • Metropolitan Museum

    0.53 miles

  • Loeb Boathouse Parking Lot

    0.58 miles

  • Quik Park

    0.67 miles

  • Motorgate Public Parking Garage

    0.78 miles

  • Knickerbocker Plaza Car Park

    0.87 miles

  • Astor Terrace Parking Garage

    0.96 miles

  • Central Parking

    1.11 miles

  • Alpha Garage

    1.12 miles

  • Ronald McDonald House New York

    0.29 miles

  • The Carlyle

    0.30 miles

  • The Surrey

    0.35 miles

  • The Mark

    0.37 miles

  • The Gardens Sonesta ES Suites

    0.53 miles

  • Plaza Athénée

    0.59 miles

  • The Franklin

    0.63 miles

  • The Palladin

    0.66 miles

  • Lowell Hotel

    0.67 miles

  • Loews Regency

    0.72 miles

  • Nordstrom

    0.08 miles

  • Gristedes

    0.11 miles

  • Morton Williams

    0.13 miles

  • D'Agostino

    0.15 miles

  • Daona Market Place

    0.25 miles

  • Target

    0.26 miles

  • A Matter of Health

    0.26 miles

  • Whole Foods Market

    0.32 miles

  • Agatha & Valentina

    0.32 miles

  • Ouri's Market

    0.36 miles

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