True
Space Available For Lease 1
Full Building |
- High traffic count address - 1 block from SSM St. Josephs Hospital, 2 Blocks from historic Main St. - Minutes from I-70 ![]()
Tom Palitzsch
Thomas Realty Group |
Contacts

Thomas Realty Group
Property Details
- Property Type Office - Medical Office
- Property Size 2,700 SF
- Lot Size 0.27 Acre
- Year Built 1985
- Date Updated Jul 2, 2025
- High traffic count address
- 1 block from SSM St. Josephs Hospital, 2 Blocks from historic Main St.
- Minutes from I-70
Reach out to the broker for more info on lease terms and amenities
Getting around
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Walk Score ®
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Bike Score ®
Location
- City Saint Charles, MO
- Zip Code 63301
- Market St Louis
Points of Interest
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Lambert Airport Terminal 2
7.71 miles
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QuikTrip
0.71 miles
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Phillips 66
1.96 miles
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Mobil
1.98 miles
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Electrify America
2.12 miles
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Tesla Supercharger
2.37 miles
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MotoMart
2.41 miles
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Love's
2.45 miles
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BP
2.46 miles
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EVgo Charging Station
7.43 miles
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Saint Josephs Hospital Parking Garage
0.38 miles
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Rideshare Pickup/Dropoff Lot
2.28 miles
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Commuter Parking Lot
2.34 miles
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Handicap Parking
2.42 miles
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Truck Parking
2.52 miles
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Fox Hill Trails Parking
2.58 miles
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MO 94/Muegge Commuter Lot
3.05 miles
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Fountain Lakes South
3.67 miles
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Heritage Museum Parking
3.72 miles
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Country Inn & Suites, St. Charles, MO
0.41 miles
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Best Western Plus the Charles Hotel
0.55 miles
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Comfort Suites St Charles-St Louis
0.59 miles
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Americas Best Value Inn & Suites St. Louis, St. Charles Inn
0.61 miles
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Ameristar Hotel
0.70 miles
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Drury Inn & Suites
0.74 miles
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Fairfield Inn Saint Charles
0.80 miles
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Embassy Suites
0.90 miles
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Tru by Hilton St. Charles St. Louis
0.95 miles
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InTown Suites
1.28 miles
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ALDI
0.50 miles
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Schnucks
0.73 miles
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Walmart Supercenter
2.13 miles
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Dierbergs
2.46 miles
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Save-A-Lot
2.71 miles
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Target
3.80 miles
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Marsell's Market
4.11 miles
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POWERplex STL
4.17 miles
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Walmart Neighborhood Market
4.91 miles
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Kohl's
6.06 miles
721 S 5th St Listing Brief
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Leasing rates here can depend on a variety of factors, including the quality rating of the property (property class or building class), the position of the available space within the building, any unique attributes that the listed space may include, as well as on the availability of on-site or nearby amenities. Reach out using the contact form available on this page to schedule a tour or to get more detailed information on the most modern facilities and amenities that 721 S 5th St has to offer.
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See the listing area details for information and ratings regarding the degree of walkability in the neighborhood, the accessibility and frequency of public transit options, as well as the level of availability and quality of biking infrastructure in the area. What’s more, you can use the interactive map for a good overview of the area. Location details also include a breakdown of distance from the property to several essential amenities and points of interest, which may include parking facilities, fuel stations, stores, or hotels.
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The building includes 2,700 square feet, of which 2,700 square feet is rentable office space.
Access more in-depth information about this property — including ownership, tenant details, property characteristics and transaction history, along with local market insights and much more — on CommercialEdge.

Thomas Realty Group