Map of Property

500 William St

For Lease

500 William St, Cape Girardeau, MO 63703

500 William St currently offers 5 industrial space(s) for rent. The property type is designated as industrial. Use types among leasing opportunities at this property include warehouse/distribution, manufacturing and flex - industrial. The minimum space size listed is 2,093 square feet. Lease type options include Full Service. Expand the individual listing section(s) below or reach out to the property representative(s) for additional information on leasing opportunities at 500 William St.

Space Available For Lease 5

Contacts

Matt Huber

Lorimont Commercial Real Estate

Property Details

  • Property Type Industrial - Warehouse/Distribution
  • Property Size 29,752 SF
  • Lot Size 1.5 Acre
  • Date Updated Jun 6, 2026
  • HVAC None
Situated in the heart of Cape Girardeau's industrial corridor, 500 William Street offers convenient access to major transportation routes, suppliers, and workforce populations throughout Southeast Missouri, Southern Illinois, and Western Kentucky. The property's central location provides efficient connectivity to Interstate 55, US Highway 61, and regional logistics networks, making it an ideal location for manufacturing, assembly, distribution, and industrial service operations.Flexible industrial space available for lease at 500 William Street in Cape Girardeau, Missouri. The property offers approximately 11,000 SF of total industrial space that can be leased in its entirety or demised into four individual suites ranging from approximately 2,000 SF to 3,300 SF. (make sure to check out the "Spaces" tab above to see each space) Designed for manufacturing and industrial users, the facility features commercial-grade power infrastructure, heavy-duty concrete floors capable of supporting machinery and equipment, and access to a shared loading dock with dedicated loading capabilities for each tenant. The flexible configuration allows tenants to lease only the space they need today while maintaining the opportunity to expand as operations grow. This property is ideally suited for manufacturing, fabrication, assembly, warehousing, distribution, contractor operations, and other industrial users seeking functional space in a strategic Cape Girardeau location.
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Highlights

  • Centrally located in Cape Girardeau
  • Commercial-grade electrical service
  • Dedicated dock door access for tenants
  • Excellent access to regional transportation corridors
  • Flexible expansion opportunities within the building
  • Four available industrial suites ranging from approximately 2,000 SF to 3,300 SF
  • Functional industrial layout
  • Heavy-duty concrete floors designed for industrial equipment and machinery
  • Ideal for manufacturing, fabrication, assembly, and distribution users
  • Lease individual suites or the entire facility
  • Manufacturing and industrial-zoned facility
  • Rare small-bay industrial leasing opportunity
  • Shared loading dock access
  • Suitable for owner-operated businesses, startups, and expanding manufacturers
  • Up to approximately 11,000 SF available

Attachments

Getting around

  • 64/100

    Walk Score ®

  • 55/100

    Bike Score ®

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Location

  • City Cape Girardeau, MO
  • Zip Code 63703

Points of Interest

  • Gordonville

    8.90 miles

  • Jackson

    9.41 miles

  • Iron Moountain Junction

    9.62 miles

  • Kidd's gas station

    1.61 miles

  • Rhodes

    2.69 miles

  • Mobil

    3.19 miles

  • Rhodes Travel Center

    4.66 miles

  • Ram's Car Wash

    5.76 miles

  • Kenny's Flippin Burgers

    0.40 miles

  • Port Cape Girardeau Restaurant and Lounge

    0.47 miles

  • Hardee's

    1.34 miles

  • McDonald's

    1.39 miles

  • Arby's

    1.48 miles

  • Fazoli's

    1.54 miles

  • Wendy's

    1.54 miles

  • Watami Sushi & Hibachi Steakhouse

    1.55 miles

  • Long John Silver's

    1.55 miles

  • Captain D's

    1.56 miles

500 William St Listing Brief

  • The rental rate for available space here starts at $$8.50/SF/YR. The asking price for this type of property can vary based on the location of the asset, as proximity to transportation hubs, access to highways or ports plays a key role in the building's valuation. Other factors that influence cost are the property age, its quality rating (building class or property class), as well as its on-site facilities and features.

  • A single-tenant industrial space is typically ideal for businesses or organizations that require exclusive and dedicated use of the entire facility. This type of space suits industries or activities that demand specialized infrastructure, privacy, and control over the entire premises.

    Multi-tenant space is ideal for businesses that need smaller spaces or that want to share the property with other businesses. The property has a variety of smaller units available, ranging in size from 2,093 to 10,992 square feet.

  • Reach out to listing brokers or property representatives using the contact form available on this page, to find out more about climate control and other essential systems at this property. Climate control is typically used in industrial buildings where businesses store items that are susceptible to temperature and humidity damage, such as food, pharmaceuticals, paper, textiles, and electronics.

Contact Listing Broker
Matt Huber

Lorimont Commercial Real Estate

  1. 1Main information
  2. 2Extra information
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