Map of Property

Historic Downtown Harrison Avenue Corner Drug Store Retail Location - Up to 12,700 SF For Lease

For Lease

485 Harrison Avenue, Panama City, FL 32401

You can currently find 2 retail space(s) available for lease at Historic Downtown Harrison Avenue Corner Drug Store Retail Location - Up to 12,700 SF For Lease. Designated use type for space listed here includes retail and street retail. Current retail listings at this property total 15,200 square feet. Lease type options include NNN. Expand the listing and property details below for additional information on leasing opportunities at Historic Downtown Harrison Avenue Corner Drug Store Retail Location - Up to 12,700 SF For Lease.

Space Available For Lease 2

Contacts

broker
Kevin Wattenbarger

Five Bridges Real Estate Services

Property Details

  • Property Type Retail - Street Retail
  • Property Size 12,700 SF
  • Lot Size 0.19 Acre
  • Property Tenancy Single Tenant
  • Year Built 1930
  • Year Renovated 2019
  • Date Updated Aug 4, 2025
Positioned at the corner of Harrison Avenue and 5th Street, this building benefits from excellent foot traffic, visibility, and proximity to key downtown attractions. Located just four blocks from the marina and within walking distance of downtown's revitalized shops and businesses, 485 Harrison Avenue anchors Historic Downtown Panama City's main street.485 Harrison Avenue offers a rare opportunity to lease a prominent historic retail building in the heart of downtown Panama City. This two-story, ±12,700 SF building is situated on a high-visibility corner at Harrison Avenue and 5th Street, steps from government offices, banks, restaurants, and waterfront amenities. With vintage charm, expansive storefront windows, and flexible configurations, this former drugstore has long served as a landmark in the community. Space Options Being Considered: 1. Full Building – ±12,700 SF (Two Floors) Ideal for a flagship retail or mixed-use concept Includes ±8,608 SF on the ground floor and ±4,098 SF upstairs Prominent corner signage and dual street frontage Access to both floors via internal staircase 2. Ground Floor Only – ±8,608 SF High ceilings, open retail floorplate, and natural light Move-in-ready zones with private offices, kitchen, and restrooms Excellent for retail showroom, food/beverage, or gallery use 3. Multi-Tenant Ground Floor Concept – ±2,500 to ±6,000 SF Suites Options Proposed three-suite / multi-tenant layout with units sizes ranging of approximately 2,500, 5,000 to 6,000 +/- SF combinations Each space has direct exterior access and storefront exposure Ideal for boutique shops, local service providers, or small food/beverage operators *Pricing & timeline to be determined if multi-tenant options are pursued
Want more info on this listing?

Reach out to the broker for more info on lease terms and amenities

Highlights

  • Flexible Floorplans: Options for full-building, single-floor, or multi-tenant use
  • Historic Character: Formerly the downtown corner drugstore with postcard-worthy prominence
  • Iconic Downtown Corner: Prime visibility at Harrison Avenue & 5th Street
  • Large Storefront Windows: Expansive glass line ideal for display and branding
  • Walkable Location: Surrounded by restaurants, government offices, and waterfront

Getting around

  • 72/100

    Walk Score ®

  • 54/100

    Bike Score ®

Powered by Walk Score ®

Location

  • City Panama City, FL
  • Neighborhood Downtown Panama City
  • Zip Code 32401
  • Market Pensacola

Points of Interest

  • Chevron

    0.90 miles

  • AMI Gas

    1.44 miles

  • Marathon

    2.23 miles

  • Exxon

    2.29 miles

  • Murphy USA

    2.30 miles

  • Beeline

    2.50 miles

  • Circle K

    2.52 miles

  • Harvey De Mathis Park parking

    3.54 miles

  • The Place Downtown

    0.08 miles

  • Tom's Hot Dogs

    0.10 miles

  • McDonald's

    0.31 miles

  • Bayou Joe's

    0.32 miles

  • Waffle Shoppe

    0.45 miles

  • Big Mama's Country Cooking

    0.47 miles

  • Subway

    0.64 miles

  • Dan D's Donuts

    0.88 miles

  • Slice House

    1.03 miles

  • Tally-Ho Drive In

    1.24 miles

  • Piggly Wiggly

    1.95 miles

  • Asian Oriental International Market

    1.96 miles

  • Burlington

    2.15 miles

  • Walmart Supercenter

    2.16 miles

  • TJ Maxx

    2.20 miles

  • Big Lots

    2.22 miles

  • Panama City Mall

    2.23 miles

  • Dillard's

    2.29 miles

  • JCPenney

    2.30 miles

  • Bealls

    2.41 miles

485 Harrison Avenue Listing Brief

  • A property’s location contributes to the asking rent almost as much as its characteristics do. For instance, central urban locations with high walkability or suburban locations with ample parking and easy access by car will claim higher rents but offer superior access to your customer base. Likewise, the quality of the building systems and property finishes have a significant impact on how businesses can conduct their activity there, as well as on the experience of their customers.

    485 Harrison Avenue is located in Downtown Panama City, which is home to a total of 1 listing(s). The rent for retail space at 485 Harrison Avenue is available upon request. Feel free to reach out using the contact form conveniently included on this page to find out more about what the property can offer for your business.

  • The property includes 15,200 square feet of retail space for lease. Of this total, 12,700 square feet are Retail, 2,500 square feet are Street Retail.

    Lease agreement conditions for the availability at this property include NNN.

    For more information or to schedule a tour of the property, use the convenient contact form on this page to get in touch with a representative.

  • You should keep in mind that different areas gradually build a reputation as hotspots or desirable corridors for shopping, eating, or other entertainment and consumer activities. So, while renting retail space in an area with a well-established high-end reputation might mean more customers that are more willing to spend, it will also place you in a more competitive environment.

    485 Harrison Avenue was last renovated in 2019.

    Knowing your ideal customer is essential. For your consideration, the average age of residents in Downtown Panama City is 39. The average household income here is $60,452 per year.

In-Depth Research Available for this Property

Access more in-depth information about this property — including ownership, tenant details, property characteristics and transaction history, along with local market insights and much more — on CommercialEdge.

Contact Listing Broker
broker
Kevin Wattenbarger

Five Bridges Real Estate Services

  1. 1Main information
  2. 2Extra information
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.