4596 Mission Street

For Lease

4596 Mission St, San Francisco, CA 94112

You can currently find 2 retail space(s) available for lease at 4596 Mission Street. Designated use type for space listed here includes street retail and medical office. Current retail listings at this property total 2,000 square feet. Lease type options include Full Service and Modified Gross. Expand the listing and property details below for additional information on leasing opportunities at 4596 Mission Street.

Space Available For Lease 2

Contacts

Kevin Velotta

Compass Commercial - San Francisco & Los Angeles

Property Details

  • Property Type Retail - Street Retail
  • Property Size 3,250 SF
  • Units 6
  • Lot Size 2,500 Acre
  • Year Built 1906
  • Date Updated Sep 19, 2026
The vibrant Mission district is a booming commercial hub with a rich cultural heritage, making 4596 Mission Street an ideal location for Retail or Street Retail ventures. This bustling neighborhood is known for its diverse blend of trendy boutiques, eclectic restaurants, and lively arts scene, attracting a steady flow of foot traffic. Proximity to popular attractions like Clarion Alley, Mission Dolores Park, and renowned eateries such as Tartine Bakery and Taqueria La Cumbre adds to the area's allure. With a dynamic mix of residents and tourists, the area offers a prime opportunity for retail businesses to thrive and become integral parts of the community.Property Description 4596 Mission Street is a Two story walk up, mixed use retail and medical office building in the Excelsior District in San Francisco. This is a perfect opportunity for an owner user in the dental, medical, or many types of service industries. There is an additional unit in the back patio making it an excellent value add opportunity. • Five Units- Two ground floor retail and Three Medical/Dental/Ortho Offices • 600 sf +- additional Unit Value Add Opportunity • Two of the 2nd floor spaces can be delivered vacant at COE. • Perfect for an owner user to run their own business and collect rental income from the leased spaces. • Recently built out and renovated dental/ortho units with full infrastructure in place. $700,000 +- in build out upgrades in recent years.Excellent opportunity to lease two distinct spaces at a highly visible Mission Street location. The approximately 800 SF second-floor walk-up is fully built out for dental or medical-related use, featuring a reception area, treatment room, bathrooms, and existing improvements—an ideal opportunity for a dental, medical, or professional office user seeking a ready-to-use space. The approximately 1,200 SF ground-floor space was most recently occupied by a jewelry store for over 20 years and offers charm, character, an open layout, and large display windows. The space is well suited for retail, office, showroom, or service-oriented businesses seeking strong street presence and visibility. Both spaces benefit from a prime Mission Street location with convenient access to public transportation and surrounding neighborhood amenities.
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Highlights

  • Approximately 1,200 SF ground-floor retail/office space
  • Approximately 800 SF second-floor walk-up
  • Convenient public transportation access
  • Excellent Mission Street visibility
  • Existing dental/medical build-out
  • Former jewelry store with 20+ years of occupancy
  • Open layout with large display windows
  • Reception area, treatment room & bathrooms
  • Retail, office, medical, dental & service uses
  • Two separate spaces available

Getting around

  • 96/100

    Walk Score ®

  • 85/100

    Transit Score ®

  • 66/100

    Bike Score ®

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Location

  • City San Francisco, CA
  • Neighborhood Mission Terrace
  • Zip Code 94112
  • Market San Francisco

Points of Interest

  • San Jose Avenue & Santa Rosa Avenue

    0.40 miles

  • San Jose Avenue & Santa Ynez Avenue

    0.41 miles

  • San Jose Avenue & Ocean Avenue

    0.54 miles

  • Glen Park

    0.57 miles

  • Balboa Park

    0.72 miles

  • San Jose Avenue & Mount Vernon Avenue

    0.88 miles

  • City College

    0.89 miles

  • San Jose Avenue & Lakeview Avenue

    1.03 miles

  • San Jose Avenue & Farallones Street

    1.21 miles

  • Ocean Avenue & Miramar Avenue

    1.26 miles

  • 76

    0.16 miles

  • Shell

    0.35 miles

  • Martco

    0.64 miles

  • F T I Arco Gas Station

    0.76 miles

  • Valero

    1.42 miles

  • Electrify America

    1.44 miles

  • ChargePoint

    2.95 miles

  • EVgo

    2.99 miles

  • Volta HQ Charging Station

    3.51 miles

  • San Francisco, CA - Geary Boulevard Supercharger

    4.01 miles

  • Upper Reservoir Parking Lot

    0.67 miles

  • Upper Reservoir Lot

    0.98 miles

  • Lower Reservoir Lot

    1.09 miles

  • St. Luke's Parking Garage

    1.69 miles

  • Noe Valley Farmer's Market

    1.87 miles

  • Top of the Hill Municipal Parking

    1.93 miles

  • Commodore Sloat Elementary School

    1.99 miles

  • McDonald's Customer Parking

    2.02 miles

  • West Portal/14th Avenue Lot

    2.06 miles

  • Burger King Parking

    2.16 miles

  • El Gran Taco Loco

    0.03 miles

  • Mexico Tipico

    0.03 miles

  • Round Table Pizza

    0.09 miles

  • Los Planes de Renderos

    0.14 miles

  • Zabb Cuisine

    0.14 miles

  • The Salad Place

    0.15 miles

  • Taqueria Guadalajara

    0.28 miles

  • El Farolito

    0.28 miles

  • Subway

    0.31 miles

  • Mission Noodle House

    0.32 miles

  • Safeway

    0.40 miles

  • Manila Oriental Market

    0.50 miles

  • Canyon Market

    0.64 miles

  • Pho Tot

    0.66 miles

  • Buddies Market

    0.68 miles

  • Whole Foods Market

    1.08 miles

  • All Fresh Market

    1.30 miles

  • Fruit Barn

    1.34 miles

  • Big Lots

    1.50 miles

  • Target

    2.30 miles

4596 Mission St Listing Brief

  • A property’s location contributes to the asking rent almost as much as its characteristics do. For instance, central urban locations with high walkability or suburban locations with ample parking and easy access by car will claim higher rents but offer superior access to your customer base. Likewise, the quality of the building systems and property finishes have a significant impact on how businesses can conduct their activity there, as well as on the experience of their customers.

    4596 Mission St is located in Mission Terrace, which is home to a total of 7 listing(s). The rent for retail space at 4596 Mission St is available upon request. Feel free to reach out using the contact form conveniently included on this page to find out more about what the property can offer for your business.

  • The property includes 2,000 square feet of retail space for lease. Of this total, 1,200 square feet are Street Retail, 800 square feet are Medical Office.

    Lease agreement conditions for the availability at this property include Full Service, Modified Gross.

    In addition to retail space, the property also includes 1 office space(s). Mixed-use buildings combining office space alongside retail present additional opportunities for steady foot traffic and a potentially loyal customer base.

    For more information or to schedule a tour of the property, use the convenient contact form on this page to get in touch with a representative.

  • You should keep in mind that different areas gradually build a reputation as hotspots or desirable corridors for shopping, eating, or other entertainment and consumer activities. So, while renting retail space in an area with a well-established high-end reputation might mean more customers that are more willing to spend, it will also place you in a more competitive environment.

    Knowing your ideal customer is essential. For your consideration, the average age of residents in Mission Terrace is 43. The average household income here is $135,119 per year.

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