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Space Available For Lease 6
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Suite 106 (Contiguous up to 13,505 RSF) • Space Available: 8,247 SF • Lease Rate: $4.95/SF • Lease Type: NNN • Suite Description: Shell space ready for tenant customization.
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Suite |
Suite 110 • Space Available: 5,258 SF • Lease Rate: $4.95/SF • Lease Type: NNN • Suite Description: Shell space ready for tenant customization.
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Suite |
Suite 115 • Space Available: 2,015 SF (Contiguous up to 11,829 SF) • Lease Rate: $5.25/SF • Lease Type: NNN • Suite Description: Call broker for details
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Suite 116 • Space Available: 2,430 SF • Lease Rate: $5.25/SF • Lease Type: NNN • Suite Description: Shell space ready for tenant customization.
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Suite |
Suite 308 (Divisible to 5,000 RSF) • Space Available: 12,308 SF • Lease Rate: $4.80/SF • Lease Type: NNN • Suite Description: Shell space ready for tenant customization.
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Suite |
Suite 315 • Space Available: 5,000 SF - 11,642 SF • Lease Rate: $4.80/SF • Lease Type: NNN • Suite Description: Call broker for details
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Contacts
MedWest Realty
MedWest Realty
MedWest Realty
Property Details
- Property Type Office - Medical Office
- Property Size 76,671 SF
- Lot Size 3.23 Acre
- # of Floors 3
- Property Tenancy Multi-Tenant
- Building Class B
- Year Built 1980
- Date Updated Mar 19, 2026
Newport Irvine Medical Center
3300 Irvine Avenue, Newport Beach, CA 92660
Premier practices warrant premiere real estate. The Newport Irvine Medical Center is poised to emerge as one of Orange County’s leading medical office buildings. This state-of-the-art facility has been meticulously designed to meet the expectations of the area’s affluent consumer groups, offering a unique and superior experience for both patients and medical professionals.
The building is being transformed to offer a rare opportunity to lease new Class A construction, including large medical office spaces, in the highly sought-after Newport Beach submarket. Newport Irvine Medical Center welcomes a range of users from solo providers and large group practices, to new ambulatory surgery and imaging centers.
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Property Features:
DESIGN FEATURES
• Grand entrance with new 3 story atrium
• Floor to ceiling glass lines to allow a continuous flow of natural light throughout the building
• Centralized stairwells creating a wellness focused environment and limiting reliance on elevators
• High quality finishes with subtle accents for an elevated aesthetic
PROMINENT LOCATION & ACCESSIBILITY
Located in a proven successful medical market with high growth, the site offers excellent accessibility from 3 major thoroughfares:
• Laguna Freeway (SR-133)
• State Route 55 (SR-55)
• San Diego Freeway (I-405)
• Minutes from John Wayne Airport, ideal for destination medicine
IDEAL MARKET & SITE LOCATION
The location is able to conveniently serve a population of 1.3 million and growing (within a 15 minute drive time) due to the quality of the roads, major thoroughfares, accessibility of the site, and unparalleled quality of life.
The service is expected to grow by 20,000 people per year.
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6 Suites Available:
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Reach out to the broker for more info on lease terms and amenities
Attachments
Getting around
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60/100
Walk Score ®
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36/100
Transit Score ®
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67/100
Bike Score ®
Location
- City Newport Beach, CA
- Neighborhood Santa Ana Heights
- Zip Code 92660
- Market Orange County
Points of Interest
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Tustin Metrolink Station
5.30 miles
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Tustin
5.31 miles
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Irvine
8.28 miles
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Orange
9.02 miles
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Chevron
0.19 miles
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Arco
0.55 miles
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ChargePoint
1.29 miles
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Irvine - Michelson Drive Supercharger
2.11 miles
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Irvine - Main Street Supercharger
2.28 miles
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Shell
2.36 miles
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76
2.48 miles
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Superior Stations
2.49 miles
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eVgo
2.64 miles
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EVgo
2.91 miles
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Cell Phone Waiting Lot
1.15 miles
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UCI Health Medical Campus - Parking Garage
1.22 miles
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University Park And Ride
1.23 miles
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UCI Health - Parking Structure
1.26 miles
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Orange County Fairgrounds Gate 8
1.28 miles
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Health Sciences Parking Structure
1.79 miles
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Lot 14A
1.82 miles
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Lot 14
1.86 miles
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Von Karman Towers Parking Structure
1.87 miles
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Mesa Parking Structure (MPS)
1.88 miles
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Ayres Hotel
0.49 miles
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Travelodge Orange County Airport/ Costa Mesa
0.62 miles
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Newport Beach Marriott Bayview
0.67 miles
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Radisson Hotel Newport Beach
0.91 miles
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Renaissance Newport Beach Hotel
1.03 miles
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Best Western Plus Newport Mesa Inn
1.08 miles
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Extended Stay America - Orange County - John Wayne Airport
1.14 miles
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BLVD Hotel, Ascend Hotel Collection
1.40 miles
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Hilton Irvine/Orange County Airport
1.43 miles
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Atrium Hotel
1.50 miles
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Ralphs Fresh Fare
1.29 miles
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Mitsuwa
1.58 miles
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Stater Bros. Markets
1.90 miles
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Mother’s
2.00 miles
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Stater Bros.
2.14 miles
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Bloomingdale's
2.15 miles
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Saks Fifth Avenue
2.21 miles
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Macy's The Men's Store
2.25 miles
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TJ Maxx
2.27 miles
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South Coast Plaza
2.27 miles
3300 Irvine Avenue Listing Brief
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Leasing rates here can depend on a variety of factors, including the quality rating of the property (property class or building class), the position of the available space within the building, any unique attributes that the listed space may include, as well as on the availability of on-site or nearby amenities. Reach out using the contact form available on this page to schedule a tour or to get more detailed information on the most modern facilities and amenities that 3300 Irvine Avenue has to offer.
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See the listing area details for information and ratings regarding the degree of walkability in the neighborhood, the accessibility and frequency of public transit options, as well as the level of availability and quality of biking infrastructure in the area. What’s more, you can use the interactive map for a good overview of the area. Location details also include a breakdown of distance from the property to several essential amenities and points of interest, which may include parking facilities, fuel stations, stores, or hotels.
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This property is in the Santa Ana Heights neighborhood of Newport Beach and located within zip code 92660.
3300 Irvine Avenue was originally completed in 1980 and is rated class B. The building includes 76,671 square feet, of which 50,442 square feet is rentable office space.
