Map of Property

2100 SIXTEENTH

For Lease

2100 16th Avenue South , Birmingham, AL 35205

The total number of office spaces available at 2100 SIXTEENTH is 12. Leasing opportunities in the building include office and medical office. There is a total of 44,220 square feet of space currently available for rent at this address. Of this, the minimum divisible area is 1,359 square feet.

Space Available For Lease 12

Contacts

Philip A. Currie

JH Berry Commercial Real Estate

Property Details

  • Property Type Office - Medical Office
  • Property Size 53,170 SF
  • Lot Size 1.26 Acre
  • Building Class B
  • Year Built 1982
  • Date Updated May 14, 2026
2100 SIXTEENTH is prominently located in Birmingham’s Southside/Medical Center submarket, offering convenient access to UAB, UAB St. Vincent’s Hospital, and Children’s of Alabama, with direct connectivity to the Red Mountain Expressway. The property is under new ownership and scheduled for exterior and common area renovations in Spring 2026. With strong surrounding institutional anchors, on‑site parking, and flexible layouts, the building is well positioned for medical and professional office tenants.2100 SIXTEENTH is prominently located in Birmingham’s Southside/Medical Center submarket, offering convenient access to UAB, St. Vincent’s Hospital, and Children’s of Alabama, with direct connectivity to the Red Mountain Expressway. The property is under new ownership and scheduled for exterior and common area renovations in Spring 2026. With strong surrounding institutional anchors, on‑site parking, and flexible layouts, the building is well positioned for medical and professional office tenants.
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Highlights

  • 2100 SIXTEENTH is under new ownership
  • Building signage available
  • Conveniently located in a prime Southside / Medical Center location
  • Easy access to Red Mountain Expressway
  • Exterior & common area improvements coming Spring 2026
  • Full-floor availability
  • Large parking garage with direct building access and on-site parking lot
  • Near UAB, St. Vincent’s & Children’s Hospital
  • Well suited for medical and office users

Attachments

Getting around

  • 86/100

    Walk Score ®

  • 35/100

    Transit Score ®

  • 33/100

    Bike Score ®

Powered by Walk Score ®

Location

  • City Birmingham, AL
  • Neighborhood Five Points South
  • Zip Code 35205
  • Market Birmingham

Points of Interest

  • Birmingham

    1.36 miles

  • Chevron

    0.26 miles

  • Shell

    0.37 miles

  • BP

    0.92 miles

  • Mac's One Stop

    1.00 miles

  • Texaco

    1.00 miles

  • Mountain Brook, AL Supercharger

    1.33 miles

  • Tesla Supercharger

    2.17 miles

  • ChargePoint

    7.03 miles

  • Vulcan Trail

    0.36 miles

  • St. Vincent's Child Care Parking

    0.43 miles

  • 32-F

    0.46 miles

  • 10th Ave Parking Deck

    0.48 miles

  • UAB G-2

    0.50 miles

  • UAB G-3

    0.50 miles

  • St. Vincent's West Parking Lot

    0.53 miles

  • Zone A-2

    0.53 miles

  • UAB G-7

    0.57 miles

  • UAB Parking Deck Zone A

    0.57 miles

  • Hotel Indigo

    0.38 miles

  • Homewood Suites

    0.41 miles

  • Residence Inn by Marriott Birmingham Downtown at UAB

    0.60 miles

  • Embassy Suites

    0.61 miles

  • Hilton Birmingham Downtown at UAB

    0.63 miles

  • Courtyard by Marriott Birmingham Downtown At UAB

    0.97 miles

  • SpringHill Suites Birmingham Downtown at UAB

    1.03 miles

  • Home2 Suites by Hilton Birmingham Downtown

    1.17 miles

  • Hilton Garden Inn Downtown Birmingham

    1.18 miles

  • Grand Bohemian Hotel Mountain Brook, Autograph Collection

    1.24 miles

  • Publix

    1.10 miles

  • Piggly Wiggly

    1.31 miles

  • GreenWise Market at Lane Parke

    1.33 miles

  • The Fresh Market

    2.27 miles

  • Target

    2.29 miles

  • Gordo's Mexican food

    2.34 miles

  • Valley Avenue Plaza

    2.35 miles

  • Walmart Neighborhood Market

    2.64 miles

  • Super Ofertas

    2.68 miles

  • Big Lots

    2.78 miles

2100 16th Avenue South Listing Brief

  • Leasing rates here can depend on a variety of factors, including the quality rating of the property (property class or building class), the position of the available space within the building, any unique attributes that the listed space may include, as well as on the availability of on-site or nearby amenities. Reach out using the contact form available on this page to schedule a tour or to get more detailed information on the most modern facilities and amenities that 2100 16th Avenue South has to offer.

  • See the listing area details for information and ratings regarding the degree of walkability in the neighborhood, the accessibility and frequency of public transit options, as well as the level of availability and quality of biking infrastructure in the area. What’s more, you can use the interactive map for a good overview of the area. Location details also include a breakdown of distance from the property to several essential amenities and points of interest, which may include parking facilities, fuel stations, stores, or hotels.

  • This property is in the Five Points South neighborhood of Birmingham and located within zip code 35205.

    2100 16th Avenue South was originally completed in 1982 and is rated class B. The building includes 53,170 square feet, of which 44,220 square feet is rentable office space.

Contact Listing Broker
Philip A. Currie

JH Berry Commercial Real Estate

  1. 1Main information
  2. 2Extra information
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